Naloxone

Opioids Definition and Classification 1. Definition It is important to distinguish between opium, opiate and opioid. According to Vallejo et al. (2011, page E343), opium is a natural extract from the opium poppy, whereas opiates and opioids are its derivatives. Natural alkaloids derived of opium are generally called opiates, whereas opioids (opium-like) can be either natural or synthetic. The most common known opioids are morphine, codeine, fentanyl, hydrocodone, oxycodone, etc. (Vallejo et al.,…

suppository dosage forms. The oral formulations are Opana and Opana ER (extended release). Opana ER, but not Opana, is crush resistant, making it harder to abuse. Opana and Opana ER, do not contain acetaminophen or the abuse-deterrent medication naloxone. There is a manufacturer’s warning to avoid alcohol while using oxymorphone. Oxymorphone is gradually replacing oxycodone as one of the most sought-after painkillers to abuse. As the demand increases, so does the cost. Whereas oxycodone sells…

the addict? Could we fine the suppliers for the addict? Unfortunately, addicts and suppliers won’t have the money to pay for fines. So to create a permanent solution for the opioid epidemic, I’m proposing a law stating that if an addict has needed naloxone, then addicts are required to go to recovery, which will be free, and the addict must do some community service. If the addict doesn’t do community service, then the addict shall go to jail. Along with that, the addict must report who the…

Police are on the front lines of the opiate epidemic because of their close proximity to those who overdose. As a response to the growing number of opiate/heroin overdoses, most departments carry Naloxone in the form of a nasal spray Narcan. Narcan is a fast acting antagonist that almost instantly reverses the effects of an overdose by attaching to the opioid receptors in the brain and blocking the opium from having an effect on the nervous system. It is a miracle drug that has saved countless…

Suboxone Detoxification What is Suboxone? Suboxone is a chemical compound of naloxone and buprenorphine. The combination is used to assist in opiate addicts, for the purpose of medication aided detox. The problem with this is, however, that buprenorphine is actually, a mild opiate itself. Clinicians would say, and some still do, that buprenorphine is not able to cause a dependency because it is only a partial opiate agonist. However, the fact that there was the general assumption, that there…

antinociceptive effect of the methanol extract of Origanum majorana (MEO) leaves was assessed after intraperitoneal administration into mice. Morphine sulfate (5 mg/kg; i.p.) and diclofenac (10 mg/kg; i.p.) were used as reference analgesic agents. Naloxone (5 mg/kg; i.p.) was also tested. MEO was studied at the doses of 50, 100, and 200 mg/kg…

treatment works is that the person would first start in a clinic, then move onto someone else that has experience in the medical field like a family doctor, counselor near their living situation. This strategy has been set in motion along with making Naloxone (overdose-reversal drug) legal and over the…

History of Heroin/Opiates Treatment In order to fully comprehend the present approach to address Heroin/Opiates addiction, we first understand what is Heroin and Opiates. Dobelstein encouraged us to identify, understand and clarify the problem. It is imperative for any practitioner to first comprehend how Heroin/Opiates irrigated to become an addiction. According to U.S Dept of Health and Humans Services, opioids are biological (harvested from opium poppies) and synthetic chemicals that…

Americans suffer from it, that is thirty percent of the world’s population (Angres et al., 2015). Addiction to pain killers caused by the intake of opioids is the reason for many deaths in the nation and we must also take precautions by supplying Naloxone to people who are addicted and also to the first responses in case of an emergency. More than 38,000 people die due to overdose, this…

EMS at the site checked finger stick blood glucose which was 440 mg/dl and 8 gm of naloxone was given to the patient. Her mental status did not improve and she was transferred to emergency department. Upon her arrival, she was hypotensive to 96/54 mmHg with a heart rate of 101 beats per minute. Respiratory rate was 10 per minute, Oxygen…