Mutant

neurons and non-neural cells in the organism, C. elegans. Since, lim-7::GFP is a reporter gene that is able to be a marker for the sheath cells, researchers were able to analyze the role of the Islet protein. Voutev et al., (2009) showed that lim- 7 mutants died; when the gene is deleted in the organism, it results in lethality. The study showed, lim-7 was an important gene; the Caenorhabditis elegans are arrested early in their larval stage. This single gene is capable of affecting multiple…

by police it was found that 33 were unarmed. Adam Geller is a columnist for the Chicago Tribune. Glassner, Barry. January 2010." The Culture of Fear: Why Americans Are Afraid of the Wrong Things-Crime, Drugs, Minorities, Teen Moms, Killer Kids, Mutant Microbes, Plane Crashes, Road Rage, and So Much More." Basic Books. New York.…

The immune system is a highly integrated, diverse task force the body recruited with the sole mission of protection against invading forces of infection, pathogens and mutant cells. The immune system is always surveilling for the enemy through its ranks of innate immune cells which lack memory and specificity including, neutrophils, basophils, eosinophils and monocytes. These cells patrol and destroy anything suspicious whether they have seen it before or not and have the ability to alert higher…

Judith Thompson is correct in maintaining that a woman does not have a duty to preserve the life of her fetus/genetic child because it is ‘her body, her say’ since the child is inside of her. Arguing against the special obligations objection, a fetus being a family member to whom the mother has a special duty which she does not owe a stranger, because although it is genetically hers and it is a person and innocent, it is attached to her and if she does not want to support and take the risks and…

muscle, hypodermis, intestine, reproductive system, and a nervous system with 302 neurons, which can also be found in high level eukaryotes (RIDDLE et al. 1997). Third, mutations in the genome can be induced by chemical mutagenesis, as a consequence, mutants with the discernable phenotypes can be easily isolated. Furthermore, as the first animal to have its genome completely sequenced, with a haploid DNA content of 100 million base pairs, the availability of the whole genome DNA sequence of C.…

Research Statement Past research accomplishments. Probing the dynamics of neuronal activities is crucial to understand the complex mechanisms of the brain and related diseases. Thus, there are great demands on optogenetic indicators for neuronal activities. However, engineering desired optogenetic indicators is a well-known challenge, probably due to the delicate sensing mechanisms, and the lack of effective high-throughput screen. To tackle this, I developed several novel molecular evolution…

gene or gene product. However, there are some obstacles to such gene based therapy for osteogenesis imperfecta. Osteogenesis imperfecta in its most severe forms results from the presence of abnormal collagen molecule. This means that to cure it, the mutant allele must first be inactivated and then substituted in for its product. Researchers are still…

correcting/replacing the mutation so the cells can produce functional PDEs. This could potentially be achieved through continuous gene therapy. The correct sequence for a functional β-subunit could be inserted into the photoreceptors to replace the mutant gene. This could then enable the cells to produce a functional cGMP PDE and allow them to respond to light accordingly. However, the biggest challenge will be detecting the mutation before it’s too far gone. As seen in figure 1, the…

The basic function of Lipolysis was discovered in early 1900s [1]. However, the proteins and enzymes involved in the process took a lot of time to identify its exact function and property. Ruford Zechner, a Biochemical professor at University of Graz, made a great contribution in the area of lipid catabolism and identified the properties of several important metabolic lipases involved in each step of the triglyceride hydrolysis into fatty acids. This led to the discovery of adipose-triglyceride…

There are many factors that are considered as a potential cause of human diseases. Most of the diseases result from a complex interaction between an individuals genetic make-up, lifestyle and environmental agents that he or she is exposed to. Family history is definitely one of the most potent risk factors. A person inherits a complete set of genes from their parents as well as a vast array of cultural and socioeconomic experiences from their family. Family history is thought to be a good…