Muscle biopsy

Duchenne muscular dystrophy (DMD) is a one type of muscular dystrophy. Muscular dystrophy is a group of genetic disorders, leading to progressive muscle degeneration. People suffering from most common muscular dystrophies ,Duchenne/Becker (DMD), Myotonic (MMD), and Limb-Girdle (LGMD), experience muscles degradation overtime, leading to overall muscle weakness and decreased mobility. Statistics show that the most prevalent forms of muscular dystrophy are rare. For example in 2007 in the…

Muscular dystrophy is a group of noncommunicable diseases that is passed down through heredity lines. Noncommunicable diseases are diseases that developed in humans without other species interference and that cannot be passed between people. Muscular dystrophy can be broken up into nine major forms: Myotonic, Duchenne, Becker, Limb-girdle, Facioscapulohumeral, congenital, Oculopharyngeal, Distal, and Emery-Dreifuss. Muscular dystrophy can appear at any time in one’s life, typically in infancy or…

Hello classmates and Professor I chose to write my discussion on a disease called Polymyositis or (PM). Polymyositis is a muscle disease that involves inflammation of the muscles or associated tissues, such as the blood vessels that supply the muscles. A myopathy is a muscle disease, and inflammation is response to cell damage. PM is not a genetic disorder, although there may be genetic factors that make it more or less likely that an inflammatory myopathy will develop. In fact, in most cases…

skeletal muscles in one’s body. Currently, there are several types of MD. This research paper will focus on Myotonic Muscular Dystrophy. Myotonic Muscular Dystrophy is the most common form of MD that affects the muscles of the face, neck, and arms, has no treatment and has several ways to be diagnosed, and has a foundation that helps people who have the disease with medical situations and treatment. Affected Muscles Krajewski stated “MD causes general weakness, usually beginning in the muscles…

There is not just one blood test done for MD, but two. Both tests can be done from the same sample drawn from the patient. One test is performed for estimation of the creatine kinase level, and the second is for DNA studies. If the muscle fibers are deteriorating, then the enzyme creatine kinase will be released more often. An elevated level of creatine kinase is a sign of multiple forms of MD such as: Duchenne, Limb Girdle, Emery-Dreifuss, and faciosculohumeral dystrophy. The DNA…

neuro-muscular disease affecting people over fifty, mostly males, is characterized by progressive muscle weakness and atrophy in key muscles in the arms (forearm flexors) and the legs (quadriceps), resulting in severe disability. IBM is generally a slowly progressive disease and life expectancy isn’t significantly affected. Ted was diagnosed with IBM in 2012 when he was 68 years old, but his muscle biopsy showed that he has had it 10 to 15 years prior to the diagnosis. This displays the slow…

and the symptoms are more severe in males than in females. Symptoms of DMD include skeletal deformities, fatigue, learning and intellectual developmental delay, difficulty breathing, and heart disease. Diagnosing DMD is done through serum CPK, muscle biopsy, genetic testing, and electromyography to confirm inheritance of the gene and progression of disease. At this time, there is no cure for this devastating disease yet new treatment modalities are being created to support quality of life.…

muscular dystrophy. Muscular dystrophy is characterized by progressive muscle degeneration (Muscular Dystrophy Association). Muscle weakness appears in early childhood and progressively worsens; children with DMD are generally wheel-chair dependent by adolescence. Along with the DMD affecting the skeletal system, the cardiac muscles are also affected and result in cardiomyopathy. Cardiomyopathy is a heart disease where weak cardiac muscle prevents the heart from pumping blood efficiently.…

becomes too difficult for the patient. The patient may also benefit from using a device that will assist the patient in breathing while they are asleep. Eventually, when the muscles are severely weakened, the patient may need to use the device at all times, and may need a ventilation device. The decision to put the…

inside the lysosome (Pompe, 2010). The glycogen build up has specific effects on the muscles of the body I chose Pompe Disease because of its effects on the muscular system. Also, I feel that, because of its specific effects directly on the lysosomes of cells causing it to be a rare disorder, it does not receive enough attention.…