Monocyte

2. MONOCLONAL ANTIBODIES: 2.1. What are Monoclonal Antibodies? 2.1.1. “Clones” A clone is a group (family) of cells which come from a single parent cell that divides various times and are identical in all ways. In their structure, metabolic characteristics, functions, etc. 2.1.2. “Antibodies” An antibody is a protein which is produced by the human body’s immune system when it detects a substance that may be harmful (antigens like: bacteria, viruses, chemicals, parasites, etc). Antibodies…

Eradication of HIV There are many ways that HIV is transmitted but if the risk factors were taken out would there be as many individuals affected by this disease? If there was an immunization to protect the CD4 cells would AIDS be a syndrome anymore? Acquired immunodeficiency syndrome is not possible without the human immunodeficiency virus which is the driving force behind scientists collaborating worldwide in ending and preventing this pandemic. Etiology “The primary etiologic agent of…

Jones. Mr. Jones appeared to be in distressed. He is now using his accessory muscles to breathe, crackles are heard on auscultation and there is decreased air entry in the left and right bases. Chest X ray revealed consolidation on the left lower lobe and atelectasis in the right lower lobe. After a series of investigation in the emergency department, Mr. Jones was commenced on Normal Saline at 125 mls/hr and he was given oxygen via non rebreather mask at 10L/min. He was then transferred…

Abstract Angiogenesis is an essential process for organ growth and repair. Thus, an imbalance in this process can lead to several diseases including malignancy. Angiogenesis is a critical step in vascular remodeling, tissue damage and wound healing besides being required for invasive tumor growth and metastasis. Because angiogenesis sets an important point in the control of tumor progression, its inhibition is considered a valuable therapeutic approach for tumor treatment. Chronic liver disease…

Nanoparticles (NPs) have piqued the interest of scientists because of their distinct physical, chemical and biological properties when compared to bulk material. These differences in characteristics can be attributed to the high surface-to-volume ratio (SA:V) of NPs compared to bulk material. Since NPs have a higher SA:V than bulk material, they are more reactive than their bulk counterparts; therefore, the surface characteristics of NPs can be easily manipulated. (Xuefei et al, 2014) Metal NPs…

The Ebola virus is gaining worldwide fame due to its sensational outbreak originating from Sierra Leone. The outbreaks of the virus have been recognized and effectively dealt with in the past, but the present outbreak is becoming a overwhelming challenge. Approximately there have been 15,000 suspected cases of the disease and 6,000 confirmed deaths so far. The horrifying visual hemorrhagic symptoms caused by the Ebola virus include internal and external bleeding as well as the fear inducing…

MYCOCEPT (Mycophenolate mofetil) is the 2-morholinoethyl ester of mycophenolic acid (MPA). CHEMICAL NAME: 2-morpholin-4-ylethyl (E)-6- (4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4 enoate. STRUCTURAL FORMULA: Fig: Mycophenolate mofetil MOLECULAR WEIGHT: 433.50g/mol APPEARANCE: Mycophenolate mofetil, is a white to off-white crystalline powder. SOLUBILITY: It is slightly…

Background MS (MS) is an auto immune disease which affects neurons of the central nervous system. A neuron consists of three main parts: an axon, dendrite, and a cell body. The axon is usually myelinated with a substance known as the myelin sheath, created by oligodendrocytes. This consists of twenty percent protein and eighty percent lipid. Each oligodendrocyte creates enough myelin to wrap around several axons. The periodic gaps between the neurons are known as nodes of Ranvier, where the…

INTRODUCTION Chronotherapy is the administration of drug or treatment according to the circadian rhythm of body that give maximum therapeutic effect and minimum adverse effects. Circadian rhythm control the biochemical process and functions of the body and environmental factors such as light, temperature, food intake can influence the circadian rhythm[1]. The pathological state of the disease condition have an observed rhythm for almost all diseases like asthma, cancer , hypertension etc. This…

QUESTIONS 1. Discuss the pathophysiology of coronary artery atherosclerosis. Include discussion of risk factors associated with the development of this disease. (10 points) Coronary artery atherosclerosis is most commonly comprised of atherosclerotic fibrous fatty obstructions of the large epicardial vessels, which provide for blood flow and transport nutrients, oxygen, and elimination of metabolic waste products such as CO2, lactic acid, and hydrogen ions. Coronary artery atherosclerosis…