Monoclonal antibodies

Direct Coombs test is also called Direct Antiglobulin Test or DAT. This test is used for the detection of IgG or C3 antibodies which are attached to the RBC’s surface. These antibodies are important to be detected because they might sometimes cause anemia due to destruction of RBCs. DAT is mainly done on blood samples of newborns, especially when a newborn is suffering from jaundice. • Procedure: 1. Place the sample of RBCs to be tested in a 5 % suspension of isotonic saline. 2. Using a…

In order to elaborate on lymphedema, you have to understand what part of the body it’s affecting, along with the system of the body it affects. Lymphedema affects the lymphatic system of the body, in which is associated/responsible for the immunity of the body to fight off infections or diseases. There are many parts of the body that make up the lymphatic system, and each play an important role. The lymphatic system is a network of tissues and organs that help rid the body of toxins, waste and…

The lymphatic system is a serious of ducts, nodes, nodules and lymph vessels among other structures and components that teams up to fight off bacteria and foreign substances that enter the body. The system is part of the immune system and it relies on various types white blood cells called lymphocytes that fight off bacteria, reduce inflammation, and respond to allergic reactions. The white blood cells are produced in the marrow of the bones beginning as stem cells. The stem cells…

Chronic inflammation is usually associated with accumulation of non-degradable substances, viral infection, and autoimmune disorders. In these situations, prolonged activation of immune cells can lead to tissue destruction, fibrosis, and uncontrolled angiogenesis. Despite the eyes are immune-privileged sites, deposition of inflammatory proteins in the drusen and observation of multiple types of immune cells in AMD eyes[9] indicate that this privilege is likely revoked. The immune-privileged of…

There are many theories that explain the damage that happens in DOMS at the cellular level. The most known explanation is the accumulation of lactic acid, but this was rejected because it was shown to be unrelated to DOMS. There is the muscle spasm theory that indicates that resting activation of the muscles caused spasm that compressed the vessels, hindering blood flow and increased the sensation of pain. The connective tissue states that there is a predominance of type II fibers that increase…

Immunocytochemistry (ICC), which this lab is based on, is commonly used as a laboratory technique to anatomically observe the location of a specific protein or antigen in cells by the use of a specific primary antibody that binds to it. A staining reagent or chromagen is used to help detect certain proteins used in this experiment, called 3,3'-Diaminobenzidine (DAB). 3,3'-Diaminobenzidine (DAB) DAB, a derivative of benzene, is an organic compound, which is both chemically and thermodynamically…

An infant is born to two parents. The father has type A blood and the mother has type B blood. A sample of the infant’s blood is sent for blood typing. When the infant’s blood is subjected to forward typing, there is no agglutination. When back-typing is performed, the infant’s serum causes agglutination with both type A and type B RBCs. Which of the following is the most likely interpretation of these results? A. The infant has type A blood. B. The infant has type AB blood. C. The infant has…

For the initial entry of the virus, the ephrinB2 domain is necessary. Once entered through micropinocytosis, protease cathespin L activates the virus (12). Nipah Virus can replicate very easily in human lung fibroblasts. It can infect the surrounding cells by either cell-to-cell spread or through release of infectious particles. When monocytes get infected, they can transmigrate through the blood brain barrier to infect the brain. This could be plausible if the monocytes were inefficient in…

work together to protect the body. One of the important cells in this system are leukocytes, or white blood cells. They’re stored in the thymus, spleen, and bone marrow. When antigens are detected, cells trigger B-cells to produce antibodies. T-cells destroy any antibodies that have become infected or somehow changed. All of these cells offer the body protection against disease (Nemours 1). These are the body systems the influenza virus affects. According to RapidReferenceInfluenza.com, the…

Echinacea works by stimulating the immune system. Whereby antibiotics destroy both good and harmful bacteria Echinacea enables your body to deal with infections and viruses as they happen. Studies show that Echinacea stimulates phagocytosis, a process where white blood cells travel around the body hunting and attacking harmful micro organisms releasing chemicals and digesting them. White blood cells are a major component of the body's inbuilt quick response immune system. Echinacea increases the…