curtailed by the drug. MMPs are endopeptidases that degrade proteins of the ECM, and TIMP are their inhibitors. As expected, treatment enhanced the expression of pro-MMP-2 protein and repressed the expression of the TIMP-2 protein. Transforming growth factor-beta (TGF-beta) is a stimulator of collagen production and upregulates collagens in IPF. Nintedanib inhibited TGF-beta-induced secretion of collagens. Through these mechanisms, nintedanib promotes anti-fibrosis and slows the process of the…
The topic of intelligence can be described as one of the most controversial subjects in psychology, this is because a single definition of what intelligence is can never be agreed upon (Kleinman, 2012). Psychologists like Charles Spearman believe it to be a single ability whereas Howard Gardener believes intelligence is more than just one ability. Similarly, the concept of creativity is very hard to define as Amabile, 1996 (cited in Maley & Bolitho, 2015) states, ‘a clear and sufficiently…
(1999) argued that intelligence is not identical to what test measures and, therefore, ‘g’ factor is rather a subjective measure and…
et al., 2004). All five factors of personality are present to varying degrees within individuals, and it is principal that all five are studied in conjunction (Conard, 2006) however, agreeableness, conscientiousness and openness have shown greater correlations with Academic Performance than the remaining two factors (Poropat, 2009). A continuously replicated result in many studies concerning personality and…
a new inventory constructed to assess the pathological personality traits associated with DSM–5 PDs—the PID5—in relation to grandiose and vulnerable narcissism dimensions. An exploratory factor analysis (EFA) of a number of measures of narcissism and NPD was conducted to generate grandiose and vulnerable factors. “2 In this quote, it pretty much is saying that to diagnose someone based on the traits is difficult and that is when the personality trait comes into…
Willebrand disease is the most common bleeding disorder. It occurs when the body makes too little of the von Willebrand factor (VWF), a protein that helps blood clot, or when the VWF is misshapen and does not work the way it should. VWF is a carrier for another protein, called factor 8, that helps blood clot. When VWF levels are low or when VWF is not working properly, factor 8 levels are low as well and the body is less able to form stable blood clots. There are four major types of von…
In today’s world it seems like there is a growing number of people that are being plagued with mental health diseases. In particular Alzheimer’s appears to affect a growing number of people each year. Alzheimer’s is considered to be the “sixth leading cause of death in the United States today” (Latest Alzheimer 's Facts and Figures, 2016). While many research is being conducted to figure out the best way to combat this, there seems to be one deterrent that stands above all. This deterrent…
was changed is that the student would also be scored by creativity and wisdom skills as well. Another is that the test would not penalize the student for being uncreative or having an impractical essay, but would receive additional points if those factors stood out. His goal was to have this test be an addition to the SAT or ACT so after the student was graded on academics, he could then be graded on how he or she thinks outside of the box. During the years this project was used, SAT and ACT…
situations. (Borghans, Duckworth, Heckman, & ter Weel, 2008) As this suggests, traits are consistent and do not drastically change over time and scenario. The most commonly used personality theories are the Myers-Briggs Type Indicator and the Big Five Factor Model. For the purposes of this and related studies the BFF model has been used. This model measures Openness, Conscientiousness, Extraversion, Agreeableness and Neuroticism. (John & Srivastava, 1999) This study aims at further discussing…
Each of these elements can provide insight in the lack of support for homosexuals as it is not something one is born with but rather learned. Two studies, Lingiardi et. al. (2016) & Village and Francis (2008) examine a number of these different factors that aid in predicting homonegativity, including two that provide strong evidence for homonegativity, religion and personality. Both religion and personality have rather broad definitions and luckily the two studies view them in similar ways.…