BRMS1 PROMOTER AND METASTATIC BREAST CANCER BRMS1, a functional gene, is composed of 10 exons and ranged from 7.8kb of genomic DNA. It is a member of mSIN3-HDAC transcription co-repressor complex and resides normally in the nucleus. Product of alternative splicing, two mRNA transcripts, which are in turn translated into two distinct proteins, 246 amino acids and 290 amino acids. When the structure of BRMS1 promoter is studied, two hyper methylated cytosine-phosphoguanine (CpG)…
Additionally, HLA-B27 positive AS patients expressed the Bcl11b mRNA slightly lower relative to healthy controls (0.40 times down-regulated; P = 0.021, Figure……...). On the other side, HLA-B27-negative AS patients were expressing the Bcl11b mRNA higher, however insignificant (0.51 times up-regulated; P = 0.23, Figure….) than healthy individuals. Methylation level of Bcl11b promoter in PBMCs The methylation status of AS patients and healthy controls has been depicted in Table ……., Figure ……...…
* Used the means of terror and fear to eliminate opposition and gain information * A Gestapo-type police force (Kornbluh 158) * Intended to centralise both the gathering of intelligence and dispensing of repression (Kornbluh 158) * Aimed to eliminate opposition of all kinds (civilian dissent, political opposition, and international opposition, and internal opposition within the military government) (Kornbluh 159) Projects and measures carried out by the DINA * 13,500 were…
Anxieties: Islam Women’s Rights, and Moral Hierarchy in Java. Anthropological Quarterly, 80(1). 5-37. Davids, N. n. (2014). Muslim Women and the Politics of Religious Identity in a (Post) Secular Society. Studies in Philosophy & Education, 33(3), 303-313. Mir-Hosseini, Z. (2006). Muslim Women’s Quest for Equality: Between Islamic Law and Feminism. Critical Inquiry, 32(4), 629-645. Molloy, M. (2010). Experiencing the World’s Religions: Tradition, Challenge, and Change (5th ed.). Retrieved from…
Russian collectivism has been an enduring feature of Russian everyday life throughout its history. People trying to survive in a harsh environment tend to band together in order to survive. This has certainly been true in Russia since the Middle Ages. The factors that influenced Russia’s collectivist traits include, but are not limited to, Russia’s vulnerability to invasion, climate, and low wages. Russia's climate is critical factor in understanding the collectivism of Russia. The short…
travel much. A notable ethnocultural group must be mentioned: the qarnot (singular and adjective: qeren). They are a diasporic group that have lost their original homeland and now live all around Mir, usually shunned, scapegoated and persecuted. They share a religion, worshipping a solar deity (they hold that Mir 's sun is the eye of their god). Culturally, they 've retained a coherent identity (though it does get complicated in places) across the…
Transitioning from the Mir system to the policy of collectivisation was an important strategy for Stalin which needed to change from the outdated Mir system. With a growing industry Russia needed a large and efficient agricultural sector to support it, the urban workers and food for workers in the towns. The policy of collectivisation…
engaged in the children products retail sector. The Company’s Detsky Mir chain comprises of over 570 stores located at the territory of the Russian Federation and Kazakhstan, as well as of more than 40 ELC stores. The average store size is 1.4 k sqm and has 20-30k SKUs2. Its product portfolio consists of toys, fashion products, newborns goods, stationary, large items and others. We initiate our coverage of Detsky Mir with BUY recommendation and the 12M target price 133.4 RUB per…
The nature versus nurture argument is, and has been, one of the most hotly debated topics in modern science for decades. The argument of whether humans start out as a “blank slate” or Tabula Rasa, as opposed to being predisposed with certain environmental effects out of their control transcends even natural science and enters into the realms of philosophy and psychology. It is nearly undeniable that the ideas of Mendelian inheritance are sound theories, yet the argument for…
Joseph Stalin, a prominent member of the Bolshevik party, and later one of the most important men in the twentieth century, took control of the Soviet Union after the death of Vladimir Lenin. From the beginning Stalin, had a clear vision of the direction the Soviet Union had to take. To Stalin, the answer to strengthen Russia was rapid industrialization. After all, Marxist theory ordained that a socialist society must be highly industrialized with an overwhelming preponderance of workers.…