Microtubule

Our logic for choosing kinesin for developing CNS therapeutics is based upon our own research, which found that kinesins are transcriptionally upregulated during memory storage and that they are both necessary and sufficient to induce long-term memory storage (LTM) in the marine snail, Aplysia californica (Puthanveettil et al., 2008; Fig 1). Furthermore, other researchers have also discovered that an increase in specific kinesin function in the mouse forebrain improves working memory (Wong et al…

INTRODUCTION Cancer can be defined as a special kind of illness that occurs when the cells in a given part of a body begin to grow out of proportion than is normal. Currently, in the United States, this disease is the second leading cause of deaths. Human beings over the history have had tumors and remedies have been implemented, and others continue to be performed and studied over time (American Cancer Society, 2010). These methods of treatment include chemo-preventive methods and of late…

Introduction Alzheimer’s disease (AD) is a complex, irreversible brain disorder that causes nerve cells to die within the brain, progressively affecting dysfunction in memory and cognitive ability, behaviour and language problems (National Institute on Aging, n.d.). Primarily this disease affects older adults over the age of sixty, although it is not considered a normal part of the aging process (Dementia Alliance International, n.d.). AD is considered the most common of the dementia diseases, a…

isn’t taken care of properly it can lead to devastating traumatic brain injuries such as CTE. Chronic traumatic encephalopathy is a build up of tau protein in the brain (Cearnal). “The tau protein is a structural element of tiny tunnels, called microtubules, in the axon. These tunnels are the transport system of the cell, like a highway or railroad” (Nowinski). So that means that when the protein malfunctions the tunnels won’t work…

The focus of my case analysis is J.R., a 53 year old Hispanic male who has retired after serving 23 years in the United States Army. His hobbies include playing golf and watching sports. J.R has health insurance through Tricare and he is able to receive medications at no cost when his prescriptions are filled on the military base at which he sees his primary care provider. He is allergic to shellfish and the reactions that he experiences are hives and airway swelling. He currently smokes 1 pack…

B) as a liquid. C) covalently bound to sugars. D) coupled to ion transport. E) via endocytosis. Answer: B Topic: Concept 35.2 Skill: Synthesis/Evaluation 25) Plants contain meristems whose major function is to A) attract pollinators. B) absorb ions. C) photosynthesize. D) produce more cells. E) produce flowers. Answer: D Topic: Concept 35.3 Skill: Knowledge/Comprehension 26) A cell that is most likely to retain the ability to divide, perform metabolic functions, and…

Breast cancer in females TERMINOLOGY CLINICAL CLARIFICATION ? Malignancy that develops in the cells of the breast which proliferates uncontrollably; most commonly ductal and lobular carcinoma ? Diagnosis requires a tissue biopsy for microscopic examination to determine pathology CLASSIFICATION ? The TNM classification is used for clinical staging of breast tumors. The American Joint Committee on Cancer (AJCC) 7th edition stages breast cancer as follows:?26 ? TX: primary tumor cannot be…