Microscopy

1. Describe your prior research experience, including duration, level of independence, and methods employed. How has your research experience prepared you for graduate studies in biomedical engineering? (maximum 50 lines, 12 pt font) “It always seems impossible until it’s done”, a quote written on top of my table in lab, is one of the elements that drive my commitment to my goals. This has always inspired me to work towards achieving the goals I set and define the research experiences I had…

Goodpasture’s Syndrome, also known as Goodpasture’s Disease, antiglomerular basement antibody disease, or anti-GBM disease is an autoimmune disease affecting the lungs and kidneys. In this rare disease antibodies are formed that attack the collagen in the lungs and kidneys leading to kidney failure and bleeding in the lungs. The laboratory plays an important role in the diagnostic process of Goodpasture’s disease. Patients will experience edema, joint pain, changes of urine color, and…

Neurodegenerative diseases are distinguished by progressive neuronal cell loss with clear patterns in disparate disorders such as Alzheimer’s, Parkinson and Huntington’s. They are responsible for around 4% of fatalities worldwide and 5% of disability-adjusted life years from a non-communicable disease (NCD). Neurodegenerative disorders are not only caused by genetics but protein misfolding disorders and protein degradation by the proteasome system. These disorders continue to increase as well as…

BRIEF HISTORY For an excellent review of earlier cerebellar research, see Glickenstein 2009. Purkinje cells were discovered just a few years before Schwann proposed his Cell Doctrine. Although it is tempting to call Purkinje’s description of the cells which bear his name the first piece of evidence in support of the Neuron Doctrine, this would be stretching the truth. In reality, anatomists at the time were still debating whether neurons in the brain stood as exceptions to the Cell Doctrine.…

Case summary: A 69 years old male with known CKD and type 2 diabetes mellitus (T2DM) was admitted to hospital following a GP visit. Increased prostate-specific antigen (PSA) levels and raised creatinine levels were observed in his blood tests. Patient was referred from GP due to worsening of creatinine on a background of 2 months of increasing pedal oedema. Ultrasound scan showed no renal obstruction and a renal biopsy confirmed pANCA vasculitis. Urinalysis also confirmed presence of glucose,…

Microscopy revealed a decreased number of pyramidal neurons in the superficial layers and presence of polymorphic cells in subgranular zone of ectal limb of dentate gyrus [30]. Astrocyte damage has been shown to be associated with myelin disintegration in…

In the course of recent years, the forensic sciences have made sensational scientific leaps forward (DNA writing, physical confirmation databanks as well as new scientific instrumentation) yet researches are expected to survey the commitment of such headways on the part and effect of scientific proof in criminal case preparing. The aim of this paper is to demonstrate the use of measurement instrumentation in a murder case. It emphasises the instruments that were used in the murder. For this…

VALPARAISO UNIVERSITY College of Nursing and Health Professions Nursing 605: Advanced Health Assessment Breast Lump Case Study Jane is a 37 year old woman who presents today after finding multiple, tender breast masses last week. She reports the masses were located on the upper outer quadrant of both breasts, and were very painful. Although the pain seems to have subsided, and she no longer feels the masses, she has kept her appointment for further evaluation. She tearfully shares with you…

High temperature proton exchange membrane fuel cells (HT-PEMFCs) are a promising clean technology, especially for automobile applications.1 These devices generate electricity from the chemical reactions that occur in the anode side of the cell, using H2 as a fuel and generating heat and water as by-products.2, 3 However, experimental studies using HT-PEMFCs show that degradation of the cell can occur after certain hours of operation (around 500 hours).4 Some of the factors that contribute to the…

Figure 3. Possible reaction mechanism for the decomposition of ammonium perchlorate. Based on the findings from all of the used techniques, the species formed in the beginning are ammonium ion, oxygen and chlorine species. The decomposition products of ammonium ion were hydroxylamine, ammonia and nitrogen dioxide. The perchlorate ion loses one of the oxygen atoms and forms chlorate ion. The ammonia is lost in reaction through formation of hydroxylamine, which is formed in reaction between…