Microscopy

Case Study 1 1. This article featured in Daily mail newspaper. It has been updated on 3rd of June 2010. 2. Tekmira is the pharmaceutical company involved in the research. 3. Ebola was the disease which was being treated. The key symptom of Ebola is haemorrhagic fever and the typical outcome of Ebola is 90% death. It’s transmitted via personal contact e.g. bodily fluid such as blood and saliva. 4. The company used a small interfering RNAs which hold the virus at bay until the immune system is…

operate as separate organizations rather than going through the complexities of a merger or acquisition. Leica offers resources such as a strong brand image, representing “German engineering at its best” and is highly experienced in the field of microscopy with glass and lens expertise that has proven to be of the highest caliber. They have also been through ownership transitions before and were on the verge of bankruptcy when they were bought by Blackstone Group. Eventually, they became…

Gout is a chronic inflammatory disease that affects nearly 4% of the population in the United States (Tophi and frequent gout flares). In fact, it is the most common form of crystal-induced arthropathy, and the most common inflammatory arthopathy in men older than 40 years (Bolognia, First Consult). Gout is a deposition disease of metabolic origin caused by supersaturation of monosodium urate, or hyperuricemia. Needle-like crystals are deposited into joints, connective tissue, and the kidneys.…

anorexia, pain abdomen and headache (Akter et al., 2015). Pertinent positives: C/o cough, chest discomfort due to cough, fatigue and SOB on exertion and fever. CXR shows dense shadow in the RLL. Pertinent negatives: None. P. Diagnostics: Sputum microscopy and culture, blood chemistry and hematology, blood gases, urinalysis for legionella, blood culture and polymerase chain reaction tests (Akter et al., 2015). Rx: Antimicrobials are the cornerstone of ACP in any population. Azithromycin 500…

Figure 2.1.3 TPGS concentration and Paclitaxel solubility are directly related. Figure created by M. Varma, 200522. TPGS has been incorporated into various drug formulations partly because of its ability to overcome multidrug resistance (MDR). By inhibiting P-glycoprotein (P-gp) activity, the relative cytotoxicity of drugs such as doxorubicin, vinblastine, and paclitaxel was increased19. P-gp is a drug efflux pump, a.k.a. multidrug resistance protein 1 (MDR1), located in the cell membranes of…

Dahler, Don. “12-year-old's suicide spotlights cyber-bullying threat.” CBS Evening News. CBS Interactive Inc. 2013. Web. 30 Nov. 2015. The author Dahler writes about the suicide case of the girl named Rebecca Sedwick. Her story begins with the conflict between her and her friends because of teenagers’ problem. However, it turned into serious when her friends started bullying on the Internet. The tragedy occurred when Rebecca decided to commit suicide because she could not tolerate cyberbullying…

Human epidermal receptor 2 positive (HER2+) Breast-Cancer (Bc) is one of the most aggressive subtypes of Breast-Cancers that is found in approximately 20% of them (1,4). HER2+BC remains a major cause of morbidity and mortality in women all over the world as once the advanced or metastatic HER2+BC is developed, no treatment can stop the progression. The combination of Trastuzumab; a monoclonal antibody that blocks HER2 receptors, and Docetaxel; a cytotoxic agent, has been approved for use as…

Most modern firearms are rifled with the exception of the shotgun. The process of rifling the barrel creates unique patterns. These patterns are called tool mark impressions. The forensic technique of analyzing the impressions left on the bullet is call ballistic fingerprinting. There are two types of strations, class characteristics and individual characteristics. Class characteristics are shared by on type of gun and manufacture, for example a colt peacemaker has 6 lands and grooves left-hand…

optimization was done by maintaining all parameter values “in range” and response goal was set to “maximize” mode. The optimum parameter which was predicted by the RSM model was then validated experimentally in triplicates. 2.5. Scanning Electron Microscopy analysis of scaffold: The scaffold was examined under scanning electron microscope (SEM) (ZEISS EVO 18) under acceleration voltage of 10 kV. The uncoated sample was used for SEM…

forensic science contributed to the wrongful convictions of about half of DNA exonerations. (innocence) Though there has been a significant increase with science over the years, there are still issues with other forensic techniques, such as hair microscopy, firearm tool mark analysis, bite mark analysis, and even shoe print comparisons. (innocence) These problems create and discredit forensic science. (innocence) Over more than a two- decade period prior to 2000, the FBI and the Justice…