Microfluidics

Abstract In this article, an analytical simulation based on a new model incorporating surface interaction was conducted to study the slip phenomenon in Couette flow at different scales. The velocity profile was calculated by taking account micro-force between molecules and macro-force from the viscous shearing effect, as they contribute to the achievement of slip length. The calculated results were compared with those obtained from the MD simulation, showing an excellent agreement. Further, the…

Neuronal regeneration is a high energy demanding process however, with maturation, axonal mitochondria transport progressively declines. Mitochondria are cellular powerhouses that supply ATP; essential for neuron growth, survival, and regeneration. Motile mitochondria can become stationary and in mature axons of the central nervous system (CNS), the majority of the mitochondria become stationary with only about 20-30% remaining motile. With this reduction in mitochondrial transport, mature CNS…

There are more than 100 million animals being poisoned, burned, crippled, and abused in many other ways in the U.S every year. All these animals being tested and injured are being tested with products with chemicals in them that are extremely dangerous. Animal testing now is increasing more and more every year which ends in more animals being abused or dying from these chemicals. Even though these researchers inflict so much harm to these animals there is no law that makes it illegal for them to…

NSCLC screening microdevice Lung cancer has one of the highest incidence and mortality rates among all cancers worldwide. Many cases of lung cancer remain asymptomatic until the disease progresses to an advanced non-curable stage. Currently there are very few early detection techniques. Imaging tests such as CT scans, MRIs, and chest x-rays done on patients in response to other conditions, such as pneumonia or heart disease, can by accident detect lung cancers early in their asymptomatic form.…

Arguments for and against animal experimentation Animals have been used time and again at some stage in the records of biomedical studies. Early Greek physician-scientists, inclusive of Aristotle, (384-322 BC) and Erasistratus, (304-258 BC), accomplished experiments on dwelling animals (Franco, 2013). Likewise, Galen (129-199/217), a Greek physician who practiced in Rome and became a giant within the history of medication, performed animal experiments to increase the expertise of anatomy, body…

CRP was identified from patients with acute pneumococcal pneumonia at the Rockefeller Institute for Medical Research (Tillett and Francis, 1930), a name that reflects its reaction with the C-polysaccharide of Pneumococcus. This pentameric protein with MW 118 kDa has five non-covalently bonded and non-glycosylated identical subunits of 206 amino acids each to form a disk-shaped pentagon (Fig. 1). CRP has been proven as an early indicator of infectious or inflammatory conditions as well as a…

Imagine a child decants kerosene over a rabbit and sets it on fire. One argument could be made that this act was immoral because it could encourage the child to set other things on fire. However, another point could be made that it might help the child build traits that he did not have before (Frey 13). In 1966 the Animal Welfare Act was passed which “...regulated the sale, transportation, and handling of many animals used in research…” (Driscoll and Finley 3), but the act does not cover rats,…

The common idiomatic expression “be the guinea pig” has a controversial and deeper meaning behind it that many people don’t even realize. In society, we use the guinea pig as a symbol of being the first to try something, typically a dangerous task or unpalatable concoction. No one wants to be the guinea pig. When our friend tries an unknown food and it turns out to be delicious, there is a beneficial outcome to them being the guinea pig. Other people then eat the food and it becomes a learning…