Methotrexate

Cancer Medicine (Oncology) Cancer cells arise from different normal cells, thus when the normal cells become abnormal, it allows the cancer cells to grow out of control. Cancers can start almost anywhere in the human body, it can occur in any tissue and at any time of life, but mostly, elders have the highest risk. Cancers are called neoplasm because neoplasm is new growths that arise from normal tissue. Furthermore, there are two different characteristics of neoplasm: benign and…

Introduction: According to Drugs.com, “Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.” This includes conditions such as headaches, painful menstrual periods, toothaches, back pain, dental pain, migraines, arthritis and any minor injuries. Ibuprofen is also used to treat and reduce fever as well and is typically administered to individuals, both adults and children ages 6 months and older. Ibuprofen has been…

antibacterial [3], antitubercular [2, 4], antiprotozoal [5] , anti-candida [2, 6], anti-cancer [7], anti-AIDS [8] and anti-inflammatory [9] activities. Many scientists report quinoxalinone derivatives as non-classical analogues of the antifolic agents-methotrexate and trimetrexate, as well as the quinoxaline N-oxide with antibacterial…

based on type, age and stage of cancer. Some of the drugs for early and metastatic breast cancer are doxorubicin, rapamycin, tamoxifen, cyclophosphamide, docetaxel, transtuzumab (herceptin), pacillitaxel, carboplatin, gemcitabine, vinorelbine, methotrexate etc. 1.2 RESVERATROL: Resveratrol (trans-3, 4’, 5-trihydroxystilbene), a naturally-occurring polyphenolic compound, is highly enriched in a variety of food sources, such as…

They also recommend the concurrent use of HAART and a drug called rituximab. The suggested treatment for BL is similar to that of DLBCL. The researchers recommend the chemotherapy regimens EPOCH and cyclophosphamide, vincristine, doxorubicin, methotrexate, ifosfamide, etoposide, and cytarabine (CODOX-M/IVAC) with concurrent use of HAART and rituximab (29, 31-3). The type of NHL an AIDS patient is important in determining the type of chemotherapy drugs that he or she…

Abstract “Medical science has proven time and again that when the resources are provided, great progress in the treatment, care, and prevention of disease can occur.” (Michael Fox).The aims of this research is to present an overview that focus on the etiology, diagnosis and treatment of pulmonary, cardiac and ocular Sarcoidosis. In the area of etiophathogenesis, clinical doctors and researcher have collectively gather a better understanding of the immune response that leads to the disease as…

INTRODUCTION Chronotherapy is the administration of drug or treatment according to the circadian rhythm of body that give maximum therapeutic effect and minimum adverse effects. Circadian rhythm control the biochemical process and functions of the body and environmental factors such as light, temperature, food intake can influence the circadian rhythm[1]. The pathological state of the disease condition have an observed rhythm for almost all diseases like asthma, cancer , hypertension etc. This…

1.0 INTRODUCTION: 1.1 Oral Drug Delivery System: Oral route is the most common route of drug administration. Modern drug delivery strategies try to improve oral drug delivery.1 When a new drug is discovered, a pharmaceutical industry asks one of the first questions is whether the drug can be effectively administered for its intended effect by the oral route or not. If patient self administration cannot be achieved, the sale of drug constitute only small fraction of what the market would be…