Metformin

ABSTRACT Fenugreek (Trigonella foenum-graecum), is used widely in numerous parts of the world as herb, food, spice, and traditional medicine. Different preprations of fenugreek have been reported as an effective remedy against polycystic ovarian disease. Polycystic ovary syndrome (PCOS) is one of the most widespread hormonal disorders among women of reproductive age causing irregular menstrual cycles, histurism, miscarriage and infertility. The study will be conducted to determine…

diabetes may need insulin injections for the long term since the pancreas is unable to create insulin. Type 2 diabetes can be managed with lifestyle changes but if that does not fully work, there are many medications used to treat type 2 diabetes. Metformin is one main medication prescribed for type 2 diabetes, the medication makes the body respond to insulin. Sulfonylureas are other medications which help the body secrete more insulin. If these medications are not enough, insulin may also be…

Among the side effects, weight gain is one of the most common ones that SUs experience with SGAs. Research clearly pointed out that SUs on clozapine and olanzapine are at increased risk of weight gain compared to other antipsychotic medications. Researchers from the Clinical Antipsychotic Trails of Intervention Effectiveness (CATIE) study clearly reported from their clinical trials that SUs on olanzapine medication demonstrated a substantial increase in their weight gain, cholesterol levels, and…

CRISPR-Cas9 system: new perspectives to cancer treatment Genetic interactions screens are used to detect genetic interactions and, as a result, to provide information into the functions of each gene and their associations with other components in the cell [2]. A genetic interaction is defined as when two genes interact and generate a phenotype that was not expected in light of each of the gene’s effect [1]. In mammalian cells, most of the genetic interaction assays use RNA interference (RNAi)…

Jerry Burdette Jerry Burdette is a sixty-five-year-old male, retired, and married. He has been married three times. He has retired from work but is always busy around the house. He currently lives with his third wife. His family also helps him with anything her needs. Jerry Burdette has some medical problems mainly joint pain. Mr. Burdette is Caucasian and had no stories about the impact his race had on him. Jerry Burdette’s family is very important to him. He has been married three…

3.8mmol/L, sodium is 142 mmol/L, albumin 30g/L, hemoglobin 129 g/L, creatinine is 62 umol/L and blood urea nitrogen is 4.6 mmol/L. His current medications include Amlodipine 10mg PO daily, Insulin regular [humulin R] q6h SC as per sliding scale, Metformin 1000mg PO BID, Budesonide-formotemol 200mcg–600mcg dose inhaler (puffer) before meal and qhs, Ethambutol 400 mg PO daily, and Tiotropium Br capsule for inhalation 18mg…

1. The 48 years old Native American women presenting to the Indian Hospital is taking Lisinopril because of hypertension as one of the conditions documented in her past medical history. Hypertension is supported by the current measurements of the blood pressure readings of 165/100. Lisinopril is an angiotensin –converting enzyme inhibitor (ACE) considered as one of the first line treatment option for hypertension. The pharmacological mechanism of action for Lisinopril is to inhibit the action…

produce enough insulin called for by the system. The type 2 diabetes could be roughly managed by a monitored diet, under the absolute check of the Nutritionist or Dieticians. In addition, changing of lifestyle and Administration of some oral drugs (Metformin) might help. Rarely, some patients with type 2 diabetes might require insulin to manage illness and to reduce the risk factors of other commodities associated with the disease. Unlike type 1 diabetes, type 2 diabetes might sometimes arise…

Complications of Diabetes Mellitus Type II A 20 years old nursing student in her sophomore year, has been diagnosed with Diabetes Mellitus Type II (DMII). Although she has completed most of her science courses, she has not completed applied pathophysiology. She knew something was wrong due the signs and symptoms presented: polyuria, polydipsia, polyphagia, acanthosis nigricans, tingling of toes and fingers, progressive vision loss. Once she consulted her primary physician, , hyperglycemia…

Pathophysiology Insulin is made by special cells called beta cells that are produced by the pancreas. Insulin is used to regulate glucose for metabolism. Insulin allows glucose to enter cells and without this glucose would not enter the cells of the body and blood sugar levels would rise in the blood, resulting in hyperglycemia. This process of high sugar in the blood without metabolism will eventually develop into Diabetes Mellitus. There are two types of Diabetes, Type 1 and Type 2. Either…