Metabolic pathway

My overarching research interests focuses on delineating animal 's metabolic responses to nutrition interventions or health conditions, associated with the animal performance and quality of its derived products. I use a combination of modern analytical chemistry (liquid/gas chromatography and mass spectrometry) and bioinformatics (univariate and multivariate statistical analysis) to measure metabolites in biological samples to provide insights on physiological or pathological status and…

James, S. J., Cutler, P., Melnyk, S., Jernigan, S., Janak, L., Gaylor, D. W., & Neubrander, J. A. (2004). Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. The American journal of clinical nutrition, 80(6), 1611-1617. Article Summary Introduction Autism covers complex neurodevelopmental disorder usually evident in the early stages of childhood and is believed to be influenced by genetic and environmental factors. Abnormal metabolism…

proteins also referred to as cell-membrane bound receptors. They are mostly found on synaptic structures and are involved in neuronal activities. Ions pass down their electrochemical gradient through ion channels without the requirement of ATP or metabolic energy. Ion channels are an important component of the nervous system as activation of these channels by neurotransmitters mediate conduction across nerve synapses. Ion channels also play a vital role in exerting cellular response to toxins…

our sugar intake, but I did not know that fructose was so bad for you. Dr. Lustig believes that sugar is a poison based on observations of current obesity trends, especially in children, and based on the pathways of the chemical breakdowns of different types of sugar. He shows the different pathways that glucose, ethanol and fructose are broken down and the similarities between fructose and ethanol are shocking. Fructose is completely broken down by the liver because our body is unable to break…

Have you ever wondered how life on earth started, and whether or not it can be explained? In the video, “Can Science Explain the Origin of Life” the narrator gives evidence as to how science can explain the origin of life. Throughout the video the narrator talked about the process of evolving, being born with traits that help living things survive in the environment, how all living things evolved from a common ancestor, and the concept of DNA. To convince the audience that science can explain…

enzyme, known as Rubisco, will fix the CO2 to form a 3 carbon compound (Khan academy [accessed 2017]). This 3 carbon compound will eventually be converted to sugar and become maple syrup (Perkins and van den Berg 2009). Plants that follow this metabolic pathway are known as C3 plants (Khan academy [accessed 2017]). It is important to note that Rubisco prefers to fix carbon 12 over carbon 13; therefore 13CO2 is more likely to diffuse out of the leaf through the stoma before the Rubisco is able to…

Research Experience Metabolic Integration in Salmonella enterica: My first research experience began with a summer internship in the Bacteriology department at the University of Wisconsin, Madison, investigating the compensatory mechanisms involved in metabolic integration. The overarching goal was to identify the changes and alternative pathways required to sustain life in a Salmonella enterica strain whose thiamine (vitamin B1) biosynthetic gene, thiH, had been replaced by an equivalent…

Diabetes mellitus is a chronic metabolic disease which is characterized by hyperglycemia, glycosuria and hyperlipidemia that in the long-term increase the probability of developing diabetic complication such as macrovascular and microvascular then complication increase mortality and morbidity. In microvascular includes diabetic nephropathy, diabetic retinopathy and diabetic neuropathy. Diabetic neuropathy is one of the most common chronic complication of diabetes mellitus that develops in about…

Lucy also consume carbohydrates such as berries and oranges, (the process in which the food moves down from the mouth to the rectum is the same as above.) it is first digested mechanically by chewing. The digestion of carbohydrates begins in the mouth by salivary enzyme, amylase, the fruits starches are digested into maltose and disaccharide. As the food travels through the esophagus to the stomach, no significant digestion of carbohydrates takes place as the HCl in the stomach stops amylase…

the human body 's metabolism is originally designed to be fueled. In the words of Leonardo da Vinci, “Medicine is the restoration of discordant elements; sickness is the discord of the elements infused into the living body” (search).These two metabolic pathways control how the human body’s energy sources are used. Once in the N8tive Zone, the body will increase performance mostly due to controlled clean nutrients, balancing of hormones, and improved cell signaling. This is due to more energy…