Merck & Co.

Index Introduction 3 1. Context 4 a. The global environment 4 b. Sanofi 5 c. Genzyme 7 d. Expected synergies 7 2. First offer 8 a. The offer 8 b. Reasons of the refuse 8 c. Impact of this first offer 9 3. Agreement and plan of merger 9 a. Tender Offer 9 b. Contingent Value Right (CVR) 10 c. Acquisition financing 10 d. Financial benefits 11 4. Results 12 a. The new group’s organization 12 b. Transfer of business units 12 Conclusion 14 References 15 Introduction For 15 years, we have…

2.5. ANTIOXIDANT STATUS 2.5.1. TLC - Semi Quantitative DPPH Assay 0.2 % DPPH solution in methanol was prepared and kept in the fridge for further use. The grid space was marked with 1.0 cm2 space on an aluminum based TLC sheet (Merck silica gel 60F254) and a stock solution of all the extracts together with the standard were prepared in methanol. A series of dilutions of the stock together with the standard were prepared ranging from 400 µL to 0.01µL for the last dilution. The grid on the TLC…

EpiPens are arguably one of the most important devices for those to carry who suffer from life-threatening allergies. Recent issues of price inflations revolving around the EpiPen have been beginning to surface in the media. This certain inflation has made the public more aware of the pharmaceutical world and the loopholes of pricing. The issue of pricing in the pharmaceutical world is nothing new, but is also not very publicly known. Big name companies have been increasing their prices over the…

PRE FORMULATION STUDY: Pre formulation testing was an investigation of physical and chemical properties of a drug substance alone and when combined with excipients. It was the first step in the rational development of dosage forms. Class: -Pre formulation study can divide into two subclasses: API characterization, Compatibility study Active pharmaceutical ingredient (API) characterization:- Organoleptic evaluation:-These are preliminary characteristics of any substance which is useful in…

rifampicin were purchased from Hangzhou Dayangchem Co., Ltd., Zhejiang, China. Acetonitrile and ethanol (High performance liquid chromatography, HPLC, grade) were purchased from Merck, Germany. Sodium dihydrogen phosphate, phenylisocyanate, triethylamine, orthophosphoric acid (analytical reagent grade) and silicone oil (viscosity 10 cSt) were purchased from Sigma–Aldrich, St. Louis, USA. Size 3 hard gelatin capsules were kindly donated by Capsugel Co., Ltd., Tokyo, Japan. Fresh Milli-Q water was…

1. Why have you selected you current major? Yes; after taking accounting 2100, I soon realized that I was very good with numbers in addition to applying formulas and seeing how mathematics applied in real life business aspects. I was fascinated by the subject matter, therefore I decided to choose Accounting as my major. 2. What is career goal and how will the major that you listed translate into your major career goal? Although it is two very diverse career goals I aim to one be a Chief…

hexafluoropropylene copolymer) was supplied by Arkema, Japan. Organically modified nanoclay, C 30B with a cation exchange capacity (CEC) of 90 meq/100 g was procured from M/s Southern clay Products. Conc.H2SO4 (98% pure) used as sulfonating agent was supplied by Merck lab grade. The catalysts, Pt black for the cathode and Pt/Ru black for the anode, were purchased from Johnson-Matthey, USA. Nafion® 5 wt-% binder solution from E.I. DuPont Company was used for membrane electrode assembly. Nafion®…

overnight, from $13.50 per pill to a visceral reaction-inducing $750 per pill. Even before Shkreli’s dastardly deed, pharmaceutical manufacturers have been playing fast and loose with drug prices for years. Januvia, the diabetes pill manufactured by Merck & Co., has more than doubled in price since it’s introduction to the market just ten years ago. Gleevec, a cancer treatment manufactured by Novartis AG, was priced at $32,000 in 2001 now costs a…

Further evidence for the in-vivo anti-inflammatory activity of Nasturtium officinale Abstract: Ethnopharmacological relevance: Aerial parts of Nasturtium officinale R. Br. are used traditionally in Iran as a folk medicine in different illnesses which include bronchitis, asthma, diabetes, hypertension, and renal colic. Aim of the study: In the present study, the anti-inflammatory activity of hydro-alcoholic extract from aerial parts of N. officinale was investigated in acute and sub¬¬-acute…

As a writer, filmmaker, creative director, and communications consultant, I believe in the power of great stories to inform, educate, excite, entertain, and to open minds. I advise institutions, corporations, and individuals on communications strategy while providing the tactical tools – web content, media relations, video scripts, speeches, live events – to reach both targeted and mass audiences. At all times my work requires close collaboration, attention to process, proactive project…