Mendelian inheritance

disease affecting equally men and women? This disease affect both men and women. It can be transfer from men to men, female-to-female, female to man. For each conclusion, make sure to explain how it is supported by the pedigree. The Online Mendelian Inheritance in Man (OMIM) database http://www.omim.org/about is a frequently updated database of human genes and genetic diseases. Search for SCA1 on OMIM. Read quickly through the page to get a general idea of the types of information that can…

Charles Darwin was stuck with certain facts in the distribution of South America. He was also in the geological relations of the present to the past inhabitants of a continent. These facts threw some light on the origin of species for evolution. It was a mystery of mysterious. It was called by our great philosophers. In 1844 he enlarged into a sketch of conclusions. It seemed to him probable from the period to the present day. He also loved natural sciences of evolution. It was a lack of…

Pathophysiology: Proteus syndrome is caused by an activating somatic mosaic mutation in AKT1, a gene which encodes the well-studied serine/threonine kinase PKB/Akt .1,2 Akt is the key mediator of the PI3K signaling pathway. In response to a growth signal (e.g. IGF, EGF) and the autophosphorylation of a receptor tyrosine kinase, PI3K is recruited and activated, generating PIP¬3 molecules at the lipid membrane. These partially activate Akt and also activate PDK1/2, which complete the Akt…

Autoimmune hepatitis (AIH) is an inflammatory disorder of the liver, which was described for the first time in the 1950s by Jan G. Waldenström (Mieli-Vergani & Vergani, 2009). The exact cause of AIH is unknown (Czaja & Freese, 2002) and because of ambiguity in diagnosing the disease the exact incidence of AIH is difficult to quantify, but reported incidences range from one in 200,000 in the general population in the United States to twenty in 100,000 females in Spain (Mieli-Vergani & Vergani,…

More than two-thirds of U.S. adults are overweight or obese (FRAC). Individuals can and do choose where they eat; they also choose what they are going to eat. There are medical conditions that make it where even if you work out and eat healthy you can still be or become obese. Fitness is another choice an individual has to make in their everyday lives. People are responsible for their own health and everyday decisions. Many restaurants, including fast food, are being blamed for today’s…

Sickle cell disease is an inherited disorder that is caused by a mutation in the DNA sequences that codes for the beta chain of the hemoglobin protein. Red blood cells are, normally, flexible and round, but with the sickle cell anemia the red blood cells become sticky, rigid, and crescent shaped. The Hemoglobin protein carries oxygen in the red blood cells throughout the body. With the disease, the blood cell’s shape can cause them to get lodged in the blood vessels resulting in the obstruction…

Because there are so many diseases in the world today it is pretty much impossible to find a cure for all of them. One of the diseases that doctors have been studying and have so far, unsuccessfully found a cure for is Tay—Sachs Disease. If I were a Genetic Counselor who had to speak with a couple and inform them about their child having the disease, I would provide them with the following information and approach them as follows: Your child has been diagnosed with a disease referred to as…

About 20% volume of the mammalian central nervous system comprises of an extracellular matrix that includes proteins, proteoglycans, and glycosaminoglycans (Bignami A et.al 1993). Evolving evidence indicates that the organization and composition of this matrix change throughout the course of normal aging, during neurodegenerative diseases and following central nervous system injury and that these modifications influence a diverse range of cellular behaviors. The central nervous system…

A good portion of the opposition towards the AquAdvantage salmon comes from farmers who will possibly be ran out of business because they cannot compete. Much of what traditional farming techniques use are based upon the basic mendelian genetics that had been discovered years before GMOs or even DNA was theorized to be possible. AquAdvantage salmon was modified so that it can develop to a “growth marker… more rapidly,” which means that it very well may be a candidate for competition…

1) Natural Selection: is the process whereby organisms better adapted to their environment tend to survive and produce more offspring. 2) This can be seen in a modern example of natural selection where: Resistance to antibiotics is increased through the survival of individuals that are: o immune to the effects of the antibiotic o whose offspring then inherit the resistance, creating a new population of resistant bacteria. Thus, natural selection constantly removes those genetic alleles…