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    Hello Dr Buxbaum, Below is my weekly update for this week from 3rd Aug '16 to 5th Aug '16. 1) FMR1 5-choice training: - At the end of the 6th week of the Fmr1 rat training, we have one rat that will be presented with the challenge trials in the upcoming week. The rat running on the challenge schedules for one week performed at around 67% accuracy rate with less than 16% omissions on the baseline schedules. This performance was observed after subjecting the rat to a long ITI (8sec) schedule, a short ITI (3sec) schedule and a randomized long ITI schedule(time ranging from 5.5-9.5sec). - The challenge series for this rat would include randomized short ITI (time ranging from 0.5sec-4.5 sec) schedule, reduced stimulus (duration from 0.2sec-0.8sec) schedules and distractor (random white noise) schedule in the upcoming week. - Along with these rats that reached criterion, we have 2 rats on S8b schedule, however, there accuracy rate is around 40% with higher than 40% omissions. Difficulty in moving up and inability to perform on the set criterion may either be due to deficit in the attention or could be due to variation in the rats performance. We will run these on the S8 schedule in the upcoming week to find out whether we see any improvement or the rats are unable to perform well even after long exposure to the schedule. - In addition, 6 rats on S7b schedule are performing at 66% accuracy and have varying omissions; though the average omission rate is less than 25%. The 3…

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