Melanocyte

explain the illness process of losing the pigment cells. Only 1% of the population affected by this illness, so it is a rare condition. Vitiligo is a skin disorder that missing a pigmentation in the skin. In addition, the pigment of the skin (melanocytes) are destructed, and this process can occur and…

The study explains a mutation in MC1R-RHC encourages a cancer-causing pathway when red-haired people are exposed to UV radiation. The MC1R, which helps with tanning od the skin, usually is primary in protecting melanocytes from damaged DNA. The researcher worked on a series of experiments that provided that in normal circumstances, MC1R would bind to the tumor suppressor gene PTEN. PTEN acts against cancer and without it, the cancer-causing pathway opens. They found…

This paper will touch on how normal cells become cancerous cells through the damaging of DNA. It will thoroughly explain the layers of the human skin. Then the paper will go in more details about a complex interaction of environmental (exogenous and endogenous), including genetic, risk factors in developing malignant melanoma. It will touch on the familial melanomas occur in a familial setting related to mutation of the CDKN2A gene as that encodes p16.4 The purpose of this project is to…

This novel route, have several characteristics to distinguish them from the more traditional target specific route available. The difference between normal skin and the lip skin. The labial skin on our lips looks clearly different from the rest of our body [38]. That is because it is much thinner in comparison to normal skin. Skin is divided in three separate layers - the stratum corneum, the epidermis and the dermis [39]. The protective stratum corneum is the outer layer that we can see, the…

condition in which a loss of cells that give color to the skin melanocytes results in smooth, white patches in the midst of normally pigmented skin. It is a common disorder that is caused by the loss of pigment in the skin. Melanin is the pigment that gives the skin its color, so when you lose some pigment in the skin you will see a change of color in your skin. That's due to the destruction of pigment forming cells known as melanocytes. People with vitiligo seem to inherit a genetic…

The largest human organ is the human skin, which covers a humans outer being. The general shape of the human skin is much like elastic flat bread stretched to fit an entire skeleton. The human skin resides in the outer realm of the human body like nails. The skin functions as a protection from the elements such as microbes, helps regulate body temperature. Without the skin and nerves could not feel sensations such as heat and cold. Why is touching important? According to Tracy Connor, touching…

causes. Your skin is comprised of cells known as melanocytes. These cells produce a pigment known as melanin, which gives skin its natural colour. The total number of melanocytes that are present in your skin eventually determines the colour of your skin. Besides giving skin its colour, melanin offers protection to the skin from the damaging effects of sunrays. The more the skin is exposed to rays of the sun, the more the melanin is produced by melanocytes. This excess quantity of melanin is…

Introduction Cancer is a disease whereby cells undergo changes that cause them to grow uncontrollably1. These changes are caused by gene mutations2. Genes are sections of deoxyribonucleic acid (DNA), contained within every cell2. Genes control which proteins are synthesised and which cells should be destroyed2. Each type of cancer is classified according to the site where the cancer initiated, i.e. the location of initial gene mutation3. Malignant melanoma is a skin cancer whereby the…

ultraviolet radiation because the melanocytes, cells in the epidermis, produce melanin which is a pigment that gives skin its color. Melanin is an absorbent of light and is able to dissipate most of the absorbed UV radiation. It is for this reason that people with more melanin, a darker skin color, have a lower rate of skin cancer than those who have less melanin. The epidermis is the outer layer of the skin and it serves to protect us from the harsh outside world. The melanocytes are found in…

Malignant melanocytes, the cells found between the dermis and epidermis that produce for skin pigmentation, proliferate uncontrollably and accumulate into melanoma tumors. In melanoma's localized stage of growth, it can be surgically removed, causing 92% of patients…