Macrophage

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  • Characteristics Of Nanoparticles

    Rats exposed to silver (Ag) NPs for 12 weeks had increased perivascular inflammation as well as chronic alveolar inflammation, alveolar wall thickening and swelling, granulomatous lesions, and alveolar macrophage accumulation (Cho et al, 2003). A parallel study found the same type of lung damage accompanied by a decrease in lung function, indicated by the tidal volume, minute volume, and peak inspiratory flow, which persisted throughout a 12-week recovery period (Song et al,…

    Words: 2262 - Pages: 10
  • Macrophage Case Study

    1. Describe what occurs when a macrophage binds to a microorganism via phagocytic receptors on the surface of the macrophage and ligands on the surface of the microorganism. When a macrophage binds to a microorganism via phagocytic receptors, there are cell surface receptors and plasma proteins that recognize the properties such as carbohydrate, lipid,or nucleic acid of the surface of the microorganism. There are also complement receptors (C3/CR4) that recognize the ligands on the microbial…

    Words: 515 - Pages: 3
  • Macrophages: A Case Study

    The main role of PMN is phagocytosis of bacteria and tissue debri. PMNs are also a major source of cytokines, especially tumour necrosis factor-alpha (TNF-α), and second population that invades the wound consist of macrophages. The function of macrophages is phagocytosis , activation and recruitment of other cells by releasing various cytokines, growth factors such as Vascular endothelial growth Factor, Insulin like Growth Factor and Epidermal Growth Factor. Macrophages regulate matrix…

    Words: 2137 - Pages: 9
  • Macrophages: Frustrated Phagocytic Analysis

    Macrophage responses to foreign material may be size and geometry dependent. Macrophages are master phagocytic cells which scour the body for foreign materials that they phagocytize and destroy. Naturally, macrophages can effectively phagocytize materials which are less than 10 μm. When material size increases (10-100 μm) single macrophages can no longer phagocytize them, instead a giant multinucleated cell called a foreign body giant cell is formed from the fusion of several macrophages in an…

    Words: 402 - Pages: 2
  • AMD Pathogenesis Essay

    achieved by formation of vascular barrier and secretion of immunosuppressive molecules[10]. RPE cells can modulate retinal immune response by secretion of immunosuppressive molecules PGE2 and PEDF to suppress T cell and macrophage activation, respectively [11, 12]. In addition, challenging RPE cells with excessive amount of preoxidized photoreceptor outer segments (Ox-POS) can induce expression of IL-8 and MCP-1 to recruit and activate immune cells[13].…

    Words: 295 - Pages: 2
  • Leishmania Tropica

    5. How does Leishmania tropica evade the immune system? Leishmania tropica surface molecule glycoprotein 63 (gp36) is found throughout the parasite surface and has the potential to degrade immunoglobulins, complement factors, and lysosomal proteins (Olivier et al. 2005). Gp36 can cleave C3b into an inactivated form and C3bi will appear on the surface of the membrane and hinders the formation of C5 convertase (Gupta et al. 2013). It is also able to use C3bi to bind to complement receptor 3…

    Words: 801 - Pages: 4
  • Case Study: Isolation And Proliferation Of MSC

    Incubation of Macrophage with MSCs 100 µl of MSC suspension (2 × 105 cell/ml) was added to each well of 96-well microplates containing macrophages and incubated for 4 h at 37°C in a moist atmosphere of 5% CO2. 2.5 Phagocytic assay by neutral red The basic phagocytic ability of macrophage (non-opsonic dependent phagocytosis) was measured by neutral red uptake. After MSCs and Macrophages were co-cultured for 2 h, 200 µl neutral red solutions (dissolved in 10 mmol/L PBS with the concentration of…

    Words: 796 - Pages: 4
  • Dietary Lipids Essay

    and migrate into the tissues where they mature into macrophages (Mosser, 2003). Tissue macrophages are spread throughout the body and designated by specific name depending on the site of tissue occupation. These macrophages are called by different names like kupffer cells, alveolar cells, microglia, peritoneal macrophages, osteoblasts, langerhans cells when they are in liver, lungs, central nervous system, peritoneal cavity, bone and skin/mucosa, respectively. They act as scavenger cells…

    Words: 4691 - Pages: 19
  • Lymphatic System

    whether that pathogen has already entered the body. In cases where the pathogen is inside the body, an internal defense is used to aid in fighting the pathogen. The body may start running a fever or start inflammation to rid itself of the pathogen. In cases where the pathogen has not yet entered the body, defenses such as tears, mucous and saliva can aid in preventing entry to the body or killing pathogens. Pathogens may also be met with natural killer cells and/or macrophages upon entrance…

    Words: 423 - Pages: 2
  • B Anthrax Essay

    (Move to treatment??) Researchers have discovered that the fight against invading B. anthracis begins with the first infected cell. They found that the impacted macrophages will instantly communicate with other immune cells to warn them of the distress and develop a strategy in order to survive. The key signaling molecule that is involved in the survival strategy is adenosine triphosphate or ATP, which is a basic currency of energy transfer used by all organisms for various biochemical…

    Words: 858 - Pages: 4
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