Lysosome

“I'm super nervous to meet the coach today” she says. She drives to practice. She meets the coach Bob. She thinks in the head the coach is kinda like the chromosomes because they teach you information about softball and how to hit a softball and catch a ball. The chromosomes In the cell Helps direct cell activity and stores necessary information for building proteins. “We are going to run a baseline drill” the coach says. (The girl) says to her friends “ isn't the baseline a little bit like the…

process by which T. thermophila obtains most of its nutrients is called phagocytosis. During phagocytosis, particles are consumed by a portion of the plasma membrane. This results in the formation of a vesicle, or phagosome, which then fuses with a lysosome in the cytoplasm to break down and digest food particles. However, a large fraction of bacteria engulfed by protozoa are not digested. Instead, they remain metabolically active and survive to be discharged to the outside environment (Aijaz…

attacked by a lysosome. Lysosomes are small specialised vesicles that hold a variety of enzymes. Their role is to digest particular molecules that enter the cell. That was a close one. You are currently experiencing a leak from your craft, of Botulinum toxin. Botulinum toxin is a neurotoxin produced by the bacterium Clostridium Botulinum. Clostridium Botulinum is a contaminant incorporated in the crafts shell and is one of the most poisonous poisons present. The cell is very lucky the lysosome…

wonder what will come next and it will keep them awake. I will bring examples about real life, for example, vacuole: Storage food, water refrigerator; Mitochondria: Battery; Endoplasmic Reticulum transport system within cell Truck transport people, Lysosomes, stomach etc. I request similar examples for the students'. This technique helps to students clarify organelles functions and compare of the real life. In order to make it most effective, we might implement the method at the end of the class…

B – dystrophin is part of a group of a protein complex that works together to strengthen muscle fibres and protect them from injury as muscles contract and relax. Dystrophin is produced by the DMD gene and mutations cause Duchenne and Becker muscular dystrophies, which lead to reduced amounts of dystrophin in skeletal muscle cells. This reduced amount of dystrophin causes muscles to weaken and damage over time, causing the build up of fat rather than muscle. This pseudohypertrophy causes the…

In contrast to other drug molecules wherein P-gp sequestration renders the drug unavailable for action, lysosomal P-gp enhanced the transport of thiosemicarbazones into the lysosomes. [28]. This accounted for the increased lysosomal damage and cytotoxicity of thiosemicarbazones towards P-gp expressing tumor cells.[28] 3.3 Inhibition of Metastasis :Metastasis accounts for the maximum deaths due to cancer. NDRG1 (N-Myc downstream…

Peripheral nerve injury (PNI) can be caused by multiple different traumas, surgical complications and diseases like diabetic neuropathy or Guillain-Barre syndrome. Patients are left with chronic pain and disability of the innervated area. Facial nerve injury is one example of PNI. Facial nerve paralysis results in unilateral facial weakness, loss of function and difficulty to speak (1, 2). Speech, mastication and expression of emotions are based on the ability to move facial musculature, which…

of ARPE-19 cultures, which was reduced by pretreatment with Borsub. Pre-treatment with Borsub reduced toxicity from menadione in ARPE-19 cell cultures. Borsub increased LC3-II conversion from LC3-I and the co-localization between LC3 staining and lysosome in ARPE-19…

Experimental Design Aim 1: Determine the amino acid sensing specificity of folliculin. Since folliculin’s novel amino acid sensing function discovery, I plan to further understand whether FLCN specifically senses a certain amino acid and if this level of detection is enough to elicit an mTORC1 response. 1.1. Determine if folliculin’s novel molecular function in amino acid sensing is triggered by glutamine. mTORC1 activation by amino acids requires FLCN where its lysosomal residence during…

Tay-Sachs disease (TSD), also called GM2 gangliosidosis, is an uncommon disorder that is genetically inherited, which progressively destroys cells in the central nervous system. The central nervous system consists of the brain and the spinal cord. Because the disorder is autosomal recessive, both parents must have the mutation in the gene in order for the child to be a carrier or have the disease. A child with parents that are both carriers has a 25 percent chance of getting Tay-Sachs and 50…