Lymphoma

cancer. Currently, four drugs are FDA approved to function as HDAC inhibitors: Vorinostat (2006), Romidepsin (2009), Chidamide (2015), and Panobinostat (2015). Vorinostat is a linear hydroxamic acid compound used against refractory cutaneous T cell lymphoma as a broad inhibitor of class I and II HDACs. By binding to the active site of class I and II HDACs, Vorinostat is able to induce the accumulation of acetylated histones and thus inducing…

Superior Vena Cava Syndrome The Superior Vena Cava (SVC) is the main blood vessel that transports de-oxygenated blood from the upper body to the heart. The SVC is a short vein located in the anterior right Superior Mediastinum, which is the area found in the mid-line of the Thorax (Drake et al. 2010). The vein is surrounded by many structures involved in the respiratory and circulatory system including the right Bronchus and the Mediastinal lymph nodes (Martini & Ivonne 2004). Figure 1 is a…

2012, their only option was a bone marrow transplant to save his life. After that transplant, his cancer came back for the third time in May 2013. Another story about this girl named Gina. Gina was diagnosed in November 2016, with Stage II Hodgkin's Lymphoma (nodular sclerosis). She had just started her second year at Massachusetts College of Pharmacy and Health Sciences where she studies Diagnostic Medical Imaging in the Sonography program which is an accelerated 3 year bachelor program. In…

chemotherapy. Venclexta is a highly selective, orally bioavailable BCL2 inhibitor that has shown activity in BCL2-dependent leukemia and lymphoma cell…

for Pennies. The all 5th period classes participated in the fund raiser, but I was actually a part of the Pasta for Pennies club that was in charge of the organization of the fundraiser. Pasta for pennies is a fundraiser through the Leukemia and lymphoma society. The money raised goes towards helping find a cure for blood cancers. I was in charge of making announcements to 5th period classes of their rating in the school compared to other classes. Another job that I had was to stay after school…

Cassandra is a 17 year old female diagnosed with Hodgkin’s lymphoma. She presents to an oncology office in Connecticut with her parents to discuss possible new treatment options and for a routine follow-up visit. Her cancer is so aggressive that your team informs her that she must continue in her chemotherapy. Cassandra’s parents are very understanding and want to continue forth in treatment using chemotherapy. The risk and benefits have been explained to the family. Opportunities for…

Immunizations are also important because of the concern with live virus vaccines and immunosuppression. Children receiving chemotherapy drugs for cancer should not receive live vaccines. Although inactivated vaccines can be given to the child with a compromised immune system delaying the vaccination is usually recommended. Family Education The nurse caring for the child with cancer has a significant supportive role in helping the family understand the different therapies, preventing or managing…

tumor clumps. Sometimes, lots of non solid tumors aggregate in an organ, and cause congestion that seems like a tumor, such as lymphoma. Therefore, being non solid does not necessarily mean absence of solid tumor; but it means the origin of cancer is a fluid, and non solid tissue. These kinds of cancers are diagnosed through blood or laboratory testing. Leukemia, and lymphoma are, respectively, dispersed cancers of white blood cells, and lymph…

Joan’s Theory Dr. Witt was negligent in failing to order an X-ray on multiple occasions, which caused injury to Joan. Issue: Did Dr. Witt treat Joan with a professional standard of care? Rule: “To establish professional medical negligence the evidence presented by the patient must show a violation of the degree of care and skill that required of a physician.” Smith v. Finch, 681 S.E. 2d 147 (Ga. 2009). Analysis: In order to establish a prima facie case against Dr. Witt, Joan will need…

Globally individuals develop and obtain disease. Among these diseases is the hepatitis B virus (HBV) and breast cancer; two commonly spread/carried diseases, and potentially life threatening diseases. Chronic hepatitis B infection alone “is a global public health issue with >350 million hepatitis B virus carriers worldwide” (Ling, W H Y et, al,1931). Breast cancer has also been on the rise infecting not only women but men as well. So, it is not uncommon for individuals to have both…