Lymphoma

Lymphoma Ryan Jones Mr. Reeves Biology Honors April 24, 2018 Introduction Lymphoma is the name of a diverse group of cancers of the lymphatic system, a connecting network of glands, organs and vessels whose principle cell is the lymphocyte. Lymphoma originated from new Latin, dating back to 1870-75; lymph-,-oma. When lymphoma occurs, cells in the lymphatic system grow abnormally. They divide too rapidly and grow without any order or control. Too much tissue is formed and tumors…

1. What is the most likely diagnosis of the underlying disease in this patient (5 marks)? Follicular Lymphoma. 2. Describe the process of autologous transplantation for the treatment of this patient’s disease. (5 marks). Stem cells are removed from patient and stored in a freezer. Patient will then receive high dose chemotherapy with or without radiotherapy to get rid of circulating tumor cells in the blood. The removed stem cells are transfused, replacing the destroyed tissue and…

The first type of Burkitt lymphoma to arise was endemic. This type has a large presence in underdeveloped countries such as central Africa and Papua New Guinea. This lymphoma was first discovered by British surgeon Denis Parsons Burkitt, which is where its name comes from (Gera, Saah, & Scott-Emuakpor, 2012, para. 2). He studied tumors in jaws of young children in African regions and found them to be caused by this unique type of lymphoma. It was in 1961 after more extensive research that he…

americans are diagnosed with Hodgkins Lymphoma each year occurring in people aged between 16 and 34 years of age and those over the age of 55. Lymphoma is a term defined as a type of cancer that develops in the lymphatic system which is part of our immune system. Hodgkins Lymphoma starts off by first developing in the white blood cells, developing in the lymph nodes and then spreading to any organ which includes the skin and bone marrow. To better understand Hodgkins Lymphoma we will take an in…

Burkitt lymphoma (BL) is an uncommon form of non-Hodgkin lymphoma (NHL), it is a cancer which affects a type of white blood cells called lymphocytes in the lymphatic system. There are three main types of BL (endemic, sporadic and immunodeficiency related). The endemic type of Burkitt’s lymphoma is considerably more common in sub-Saharan Africa, in where it has a close link to Epstein - Barr virus (EBV) and Malaria, whereas the sporadic type only has a 20% association with the EB virus and is…

Burkitt’s Lymphoma is a form of non-Hodgkin’s lymphoma in which cancer starts in the immune system called B-cells. It affects the lymphatic system, which helps your body fight infections. There are two common types: Sporadic and Endemic. The types differ by the parts of the body affected and the geographic location. Cause: The disorder is caused by chromosomal translocations. It is also associated with impaired immunity. The endemic (African) type is linked to the Epstein-Barr virus, HIV, and…

While 10% of lymphomas are Hodgkin lymphoma, the other 90% are non-Hodgkin lymphoma. Because lymphomas are so common, most specialists have found at least one in their career. And due to the different types of non-Hodgkin lymphoma, it is difficult to diagnose it correctly. Although there are a wide variety of non-Hodgkin lymphoma, they are very treatable and curable (Shankland, 2012, 848). A lymphoma is classified as a cancer in the lymphocytes, which help make up the immune system. Due to the…

Relapsed/Refractory Follicular Lymphoma By Liji Thomas, MD Follicular lymphoma (FL) is an indolent tumor of the lymphatic system which may often remain inactive for years before undergoing transformation into an aggressive tumor. After treatment, a high percentage of patients fail to respond, and these tumors are categorized as refractory lymphomas. Some respond with an initial positive change, but then develop signs of recurrent tumor, called relapsed follicular lymphoma. What causes…

1.6 Hodgkin’s Lymphoma Previous in silico research in our laboratory found that H2A.B is highly expressed in one particular cancer type, Hodgkin’s Lymphoma. Hodgkin’s Lymphoma (HL) is a type of B cell cancer that affects both men and women of various ages. HL can be divided into two classes: classical HL (cHL) and Nodular Lymphocyte Predominant HL (NLPHL) according to the WHO classification 2008 (Swerdlow et al., 2008). The classical HL accounts for 95% of all HL cases, and it has been further…

Hodgkin’s Lymphoma is a cancer of the lymphatic system. This disease affects the immune system which compromises the body’s ability to fight infection. Due to the advances in treatments, patients diagnosed with Hodgkin’s Lymphoma have an improved chance for a full recovery. A few of the risk factors for Hodgkin’s Lymphoma are as follows: an individual that is young or late in adulthood, having been infected with Epstein-Barr Virus, having a first-degree relative (parent or sibling) with…