When I think of the body’s immune system, I think of the video game Pac-Man. Pac-Man gobbles up all the little dots in his way, our body works hard to gobble up germs in its way, much the same as Pac-Man. There are also enemies that try to attack Pac-Man and attempt to make him lose a life, in the same way, our body has to defend against viruses that try to attack it. In the game, you are successful if you are able to keep Pac-Man alive by gobbling up everything in its path before they attack…
divided into two classes: classical HL (cHL) and Nodular Lymphocyte Predominant HL (NLPHL) according to the WHO classification 2008 (Swerdlow et al., 2008). The classical HL accounts for 95% of all HL cases, and it has been further divided into 4 subtypes: Nodular sclerosis cHL, which is the most common phenotype (75% of cHL cases); Mixed cellularity cHL, the second most common phenotype (15-25% of cHL cases); Lymphocyte Rich cHL and Lymphocyte Depleted cHL, which comprise 6% and…
monocytes. These cells patrol and destroy anything suspicious whether they have seen it before or not and have the ability to alert higher up the ranks to the acquired immune cells. Which have specified actions and memory and comprise of B and T lymphocytes. The acquired immune system is the secret agents of immunity and takes longer gaining information about the pathogen to devise strategy…
A JAK/STAT signaling pathway sends signals from outside the cell into the gene promoters found on DNA. The JAK/STAT signaling pathway is essential to the development of T-lymphocyte development. On the other hand, when the JAK/STAT is activated when it should not be, autoimmune diseases arise. SOCS proteins are responsible for regulating the duration and intensity of JAK/STAT signaling. In Dr. Larkin’s research, he has concluded…
Millions of people all over the world saved by the correct use of radiotherapy (1) and about 50 percent of cancer patients have at least ones in their course of treatment (2). Radiation therapy involves exposure to normal tissues as well as the tumor tissue and can cause damage to the normal cells because of the high energy of the gamma and X-ray (1). All molecules in the cell including lipids, proteins, carbohydrates and nucleic acids have potential to receive damage by radiation. However,…
Rituximab, a chimeric human and murine monoclonal antibody, targets the CD20 antigen expressed on pre-B cells and mature B-lymphocytes [55]. The antibody was originally developed for the treatment of B-cell lymphoma [56]. Recently, it has been administered for treating different autoimmune disease. As rituximab is an IgG1 subclass antibody, it crosses the placenta, interfering with fetal and neonatal B cell development and could lead to immune deficiency and raise susceptibility to infections in…
keep out and destroy these “foreign invaders”. Organs of the immune system are called lymphoid organs that have lymphocytes (small white cells that are produced in bone marrow and fight against infection). A type of lymphocytes is a T-cell; they start development in the thymus then mature to be able to distinguish between “self and nonself” cells. Following development lymphocytes are kept in the lymph nodes and spleen (contain compartments of specialized immune cells). These organs “contain…
for example body, lymphatic. In spite of the fact that these are created by lymphocytes, for example, antibodies circle unreservedly in the blood and lymph. This is where they bind essentially to extracellular targets, microscopic organisms, bacterial poisons and free infections, inactivating them briefly and making them for a pulverisation by phagocytes or supplements, (Marieb & Hoehn, 2010). At the point when lymphocytes themselves, as opposed to antibodies, guard the body, the safety is…
is important to understand the origin of AIDS-related lymphoma. According to the article “AIDS-Related Malignancies,” AIDS-related lymphoma is believed to be caused by the overproduction of B-lymphocytes, a type of white blood cell which is an important aspect of immunity. The low blood levels of T-lymphocytes, another type of white blood cell, is characteristic of HIV, and it contributes to the unusual proliferation…
Virus (HIV), which is a type of virus that attacks the body’s immune system. AIDS is a retrovirus that causes the body to become immunocompromised. This means the body attacks itself when it is unable to produce the proper lymphocytes to fight an infection (Rushing 1). Lymphocytes are cells in the body…