Lithium pharmacology

1. INTRODUCTION Warfarin is a most common Anticoagulant in prevention and treatment of thromboembolic events despite the availability of new drugs such as Novel Oral Anticoagulants due to its affordability. The establishment of the International Normalized Ratio (INR) helps to guide the dosing requirement for patients receiving the warfarin therapy. However, over-anticoagulation leads to adverse events such as haemorrhage while thromboembolic events can happen even at a recommended dose.…

CHAPTER-V FORMULATION AND EVALUATION OF LEVODOPA FLOATING TABLETS FORMULATION AND EVALUATION OF LEVODOPA FLOATING TABLETS Several approaches are currently used to retain the dosage form in the stomach. The principle of the floating tablets is simple and practically approach to achieve increased gastric residence time to obtain controlled release floating tablets designed based on the gas generating principle needs a strong floating matrix former. In this regard HPMC K4M,…

Consequences of Antigen-antibody Binding:- Interaction of antigen and antibody is a bimolecular association and it never lead to an irreversible chemical modification in either the antibody or antigen. The association between antigen and antibody includes various non-covalent interactions between the antigenic determining factor (epitope) of the antigen and the…

The invention relates to formulation of Ketorolac Tromethamine and Phenylephrine Hydrochloride immediate release tablet having less disintegration time. HPLC method was developed and validated for determination of content of Ketorolac Tromethamine and Phenylephrine Hydrochloride in immediate release tablet. UV spectrophotometric method was developed and validated to study drug release profile of Ketorolac Tromethamine and Phenylephrine Hydrochloride in immediate release tablet. Background:…

rug interactions are the harmful or beneficial effects of co administered medicinal products, these interaction may be synergistic or antogon istic pharmco kinetics or pharmaco dynamics, drug interactions exists between drugs anddrugs, drug and foods, drugs and herbs, benefits effects include convenience . Reduced toxicity and reduction. ANTIHISTIMINE, ANTIHISTIMINE, ASTHMA, ANALAGESIC, TYPHOID, HYPERTENSION, TUBERCULOSIS ANTIBIOTICS, FILARIA, RHEUMATOID ARTHRITIS, ANTIPYRITIC, ANTICANCER…

92. The client who is under the management of the nurse notes that the former is prescribed with Fluphenazine decanoate (Prolixin). Which of the following nursing Implementations applicable in caring for the client? Select all that apply. A. Assess client's temperature every 4 hours B. Monitor intake and output C. Monitor complete blood count D. Give analgesics PRN as ordered E. Ask the client to report sore throat immediately Rationale: Alternatives A, C and E are correct. Fluphenazine is a…

Pharmacokinetics is the branch of pharmacology that describes how the body affects a specific drug after administration. A number of phases occur once the drug enters into contact with the gastro intestinal wall, these are described using the acronym ADME, starting with the mechanisms of absorption, which is the process by which a substance enters the blood circulation. Distribution, where the dispersion or dissemination of substances throughout the fluids and tissues of the body. ADME also…

Medicinal Plants and their Importance According to Ketchen (2017), edicinal plants can give a life changing options for people who cannot afford expensive medications and surgeries for their ailment. Most herbal medicine focus on prevention of a certain ailment and it involves of using plants and extracts of it to give an effective and safe treatments for illnesses. People doesn’t use herbal medicines because it is cheap, some people use it because it helped to prevent in some particular…

Herbal drugs have been used since the olden days. By the term “herbal” itself, it is from the plant origin and believed to be medicines for the treatment of a range of diseases. As a matter of fact, medicinal plants have played a major role in the well-being of the world population. However, there is a decline in the widespread application of phytotherapy, observed at the end of the first part of twentieth century. Plants still make an important contribution to healthcare in spite of the great…

Abstract Dexmedetomidine is widely used for procedural sedation due to its unique combination of sedation, analgesia and anxiolysis with minimal respiratory depression. Transient hypertension has been reported during the use of dexmedetomidine which is usually benign and is taken over by the hypotensive response on continuing the infusion. We report a case of hypertensive crisis following dexmedetomidine infusion used for procedural sedation, necessitating discontinuation of the infusion and…