Alkylated polycyclic aromatic compounds (alkyl-PACs) are the major aromatic constituent of total PAH in crude oil and originated from incomplete combustion process. Whereas benzo[a]pyrene (BaP) is a well-known human carcinogen, dibenzothiophene (DBT) and retene (Ret) are not; however, all three compounds are important environmental pollutants. Their toxicity is not yet characterized. In this study, we used BaP (parent PAH), DBT and Ret (alkyl-PACs) to elucidate the mechanism of neurotoxicity…
The Nisin Bacteriocin Introduction Nisin is a bacteriosin peptide made up of 34 amino acid residues that contain uncommon amino acids such as lanthionine and didehydroalanine. It is a substance produced by both gram positive and gram negative bacteria to control the growth of other bacteria species to reduce competition for substrate and space. Nisin has received attention from researchers making it the most exploited bacteriosin (Shetty, Pometto and Levin, 2006). The attention from…
periods with little sea ice historically • Mitochondrial DNA (mtDNA) – relationships based on differences in a group of genes • The polar bear genome discovered alterations in genes related to the development of the heart, cardiovascular function and lipid metabolism – this is why they can eat massive amounts of fat without getting sick. • Evidence that there is climate change so brown bears can expand their range northward • Their anatomy and DNA shows that they are genetically closely…
the skin). Three mechanisms by which chemicals diffuse into the skin have been proposed: Intercellular lipid pathway As the name implies this process involves the movement of the hazardous chemical through a lipid pathway. The spaces of the corneocytes (cells of the stratum corneum) is the pathway through which the substances navigate through. These spaces are composed of fats, oils and lipids, as a result chemicals with a high lipo-affinity or with a lipophilic chemical nature will pass…
cells have a cell membrane made up of a bilayer of lipids that is embedded with proteins that allow wastes to exit the cell and nutrients to enter. Lipids are long chains of hydrocarbons that are essential to cell membrane growth and function. Certain enzymes speed up the process of hydrocarbon elongation. Triclosan stops the building of lipid chains by binding to the active site of the enzyme and stopping the process of elongation of the lipid chain and thus stopping the growth of the cell…
Discussion Immune reaction to viral invasion is important to combat virus growth and to minimize any damage that can be imposed on the host cells [30]. In this study, the host immune response in the bursa of Fabricius, an organ mainly colonized by B lymphocytes, was assessed upon infection by the avian virus NDV genotype VII IBS002 and genotype VIII AF2240. The cell population in the chicken bursa was evaluated by flow cytometry and the results showed that in normal chickens, this organ was…
As a final step in this experiment, we entered our data from My Fitness Pal, which then was calculated in Microsoft Excel. Carbohydrates contain 4 kcal per gram, fats 9 kcal per gram, and protein 4 kcal per gram. The total amount of carbohydrates, lipids, and carbohydrates was then multiplied by its energy density to provide the total amount of calories. Along with water intake, exercise was also factored in, which mainly involved the amount of time walking or jogging. BMI, EER, and energy…
displacement of bone or disc into the spinal cord during fracture of the spine. On the other hand secondary injury developed due to the mechanical injury involvement. It includes several biological events like – vascular changes, free radical formation, lipid peroxidation, disruption of ionic balance, glutamate toxicity, apoptosis, inflammatory response, blood flow changes and…
known as target in the production of anti-inflammatory drugs [5]. Another protein that plays a big role in breast milk is the bile salt stimulating lipase. This enzyme helps newborns and infants obtain energy from breast milk by breaking down certain lipids. Another quality that can be attributed to this protein is its part in protecting babies from certain viruses, even from HIV. It does this by binding to a group of cells, called dendritic cells, in order to prevent the HIV infection of CD4+T…
In figure 4a it shows which protein it shown in a membrane raft fraction before and after FCεRI stimulation. The figure show that it was a control test with the membrane raft fraction, and a second one with FCεRI. The proteins that was tested for was CTx, α IKK2, α SNAP-23, α Syntaxin 4, α VAMP-2. The paper wanted to see if IKK2 was going to react to stimulation of FCεRI. In the control experiment it shows that CTx was on the fifth band of membrane raft fraction. When it came to α IKK2 the band…