Diffusion is the mass of the substance that is involved. Small masses allow for a faster and easier Diffusion. Larger masses hinder the process of Diffusion and require more time and energy. Various particles move easily and “freely through the lipid bilayer of the plasma membrane”. (Tortora and Derrickson 2014) This particular passive process is called Simple Diffusion. Simple Diffusion allow for a substance to “move down its concentration gradient”. (Brown 2011) Other types of process include…
higher concentration to an area of lower concentration (Reasoner 2011). Passive diffusion and facilitated diffusion are the two major types of diffusions. Passive diffusion, also known as simple diffusion, is when particles move freely through the lipid bilayer of the plasma membrane (Tortora and Derrickson 2014). Facilitated diffusion is when and integral membrane helps the particles move across the membrane because the solutes are too highly charged to move through the plasma membrane (Tortora…
the cell material through ought the entire cell Smooth Endoplasmic reticulum is a large network of tubes running from the nucleus to the outer membrane of the cell. Its main function is to transport material to the cell and then make and breakdown lipids and…
Current studies have found that taking omeprazole (prilosec) in combination with paclitaxel, will increase the effectiveness of paclitaxel as an anti-cancer agent. Paclitaxel is an effective form of cancer therapy that treats various kinds of cancer from ovarian to lung cancer. Paclitaxel works by promoting the polymerization of microtubules and prevents depolymerization to have a cytotoxic affect on cells (DeAngelis LM, et al., 1995). Omeprazole is a proton pump inhibitor used clinically for…
can’t. The cell membrane consists of two phospholipid bilayers. Each layer has an electrically charged, hydrophilic head, while the tail is an uncharged hydrophobic. The electrically charged head of these layers face toward the water as the uncharged tails face each other. This makes it easier for small, neutrally-charged molecules to pass through the cell membrane as opposed to charged and larger molecules. Within the phospholipid bilayer there is embedded proteins which form a mosaic…
SHOULD WATER CHLORINATION BE BANNED? The recorded deaths due to waterborne diseases have demonstrated that water treatment is critical. Thus, methods like water chlorination have been developed to achieve water quality. This procedure has exhibited notable decreases in diarrhoeal diseases, and has shown prolonged disinfecting effects on many microorganisms when used with ammonia. However, there exists protozoa that are resistant to chlorination, and such spores have led to outbreaks that…
were isolating the Rh molecule, another molecule that was the size of 28 kilodaltons kept on appearing. They thought it was some part of the Rh molecule, but it turned out to be a new undiscovered molecule. Most cells move by osmosis through the lipid bilayer of cell membranes. But because of the high water permeability of some epithelial cells it was suspected, that another transport mechanism existed. The research and discovery of water channels by Agre and his colleagues, won them the nobel…
Solubility studies The solubility of docetaxel in various vehicles selected as oil, surfactant and co-surfactant for formulation of L-SNEDDS was determined and presented in the Table 1. Among the tested vehicles, Capmul PG8 NF (>250 mg/mL), Capmul MCM C8 (>250 mg/mL) and Transcutol P (>200 mg/mL) had the highest drug solubilization capacity for docetaxel. Whereas, Captex and Gelucire 44/14 shown the least solubility of docetaxel in them. Based on the solubility results, Capmul PG8 NF…
substance. It is impermeable to large uncharged polar molecules and ions, but is easily accessed by nonpolar molecules such as carbon dioxide and oxygen (which explains cellular respiration). The structural framework of the plasma membrane is the lipid bilayer, which is two layers that are…
obtainable [67,68]. Liposomes have huge skillfulness with regard to physicochemical characteristics, permitting acclimatization of the tiny particle to dovetail to the exact biological application [69]. Building blocks of the bilayer structure, of liposome, are composed of natural lipids or/and synthetic polymers and cholesterol [70]. Liposomes circulatory half life has been extended through the emergence of polyethylene glycol (PEG) which assist in the evasion…