Linkage

The LMNA gene (1q21-22, MIM 150330) encodes two proteins of the nuclear envelope – lamin A and C. They are intermediate filament proteins necessary for function and structural integrity of the nucleus. Lamins consist of an amino-terminal head domain, a coiled-coil central rod domain and a carboxy-terminal tail domain (Fig. 1A). They form dimers by rod domains and then associate in head-to-tail polymers creating complex network conjunction with other proteins located underneath the inner membrane…

three main groups (Seymour, 2002) (30). Polygalacturonase (PGase) and pectate lyase (PLase) (EC 4.2.2.2) split the molecular chains of the respective polymers (Kashyap et al., 2001) (29). Pectin methyl esterase (PME) (EC 3.1.11) hydrolyzes the ester linkage between carboxyl and methyl groups of pectin and release methanol. Endopolygalacturonase (EC3.2.1.15) and exo-polygalacturonase (EC 3.2.1.67) are the enzymes of particular interest to industry because they act on pectin, hydrolyzing its…

(Campbell 1960) date roughly around the mid-fourteenth century B.C. and the Uluburun shipwreck (Fawcett and Zietsman 2012) dates from around 1300 BC. The timeline of the two are close enough to warrant some discussion on their possible linkages. Any such existing linkages may bring clarity in our understanding of the importance of gift exchanges in the Middle East and Mediterranean in the 2nd and 1st Millennium BCE. The Amarna letters can be considered as historical evidence when it comes to…

I believe that slave narratives are one of the most important sources of information for learning and understanding the important part of American history; the slavery and its linkage with African Americans. These slave narratives don't just capacity as stories of continuance and survival, but also use a particular authorial voice which adds to their convincing force. As African-American abolitionists, the narrators of slave narratives would have felt the double weights of staying consistent…

Spinal Cord injury is the second leading cause of paralysis in the United States. Persons affected by spinal cord injury lose their independence and have a severely deteriorated quality of life due to the functional impairments in their upper and lower limbs. Various studies have revealed that specific interventions and therapies after a spinal cord injury can lead to the recovery of movement, even after severe paralysis. When the spinal cord, a thin bundle of nervous tissue, is damaged,…

Introduction I am interning at Mercy Behavioral Health Service Coordination Unit (MBH-SCU) at the Reedsdale location. The unit collectively serves 500-700 consumers, and is divided into six teams. Each team includes a supervisor and ten to fifteen service coordinators, and aid a specific population, such as adults, adolescents and children. The unit missions are to coordinate services, offer support, and empower consumers to live healthy, fulfilling lives in the Pittsburgh area.…

characterized by membranes which are “branched hydrocarbon chains attached to glycerol by either linkage” (UCMP-Archaes: Systematics, 2014). These organisms also have a unique characteristic of being able to withstand high temperatures as well as conditions which are acidic. In contrast, the bacteria domain prokaryotes’ membranes are made of “unbranched fatty acid chains attached to glycerol by ester linkages” (UCMP- Introduction to bacteria, 2014). Another unique characteristic to this domain…

Mawyr College in 1891 (Thomas Hunt Morgan, n.d.). He then became Professor of Experimental Zoology at Columbia University in 1904. Morgan had a very keen sense towards teaching. He is also known as being a successful teacher. He began to research sex linkage on the fruit fly, or Drosophila, in 1909. Before his discovery, the world had thought that the chromosomes were fully formed adults already present in the egg or sperm. People did not have the knowledge to test that theory, until Thomas Hunt…

has a vested interest in keeping the JSTARS fleet at Robins and to ensure that a new airframe is acquired. The leadership of the ANG has taken full advantage of the new political frame. Bolman and Deal (2013) state that political leaders build linkages to key stakeholders, and focus their attention on building relationships and networks (p364). The 116th ACW leadership had to ask itself a key political frame work question; do the current resource allocation processes support the new structure…

The Florida School of Deaf and Blind(FSDB) is located in St. Augustine, Florida and was established in 1882 by Thomas Coleman. This school has had a positive impact on the Deaf community with being one of the first schools in the state of Florida. FSDB has been named as one of the top deaf and blind schools in the nation; with a lot of well-known individual graduates. FSDB, I believe is very well off considering they start with pre-k and go all the way up to teaching young adults. From reading…