Ligand

The heterocyclic compounds naming tetrahydrocarbazoles having the significant biological properties. The newly substituted tetrahydrocarbazole derivatives were prepared from substituted phenylhydrazine and cyclohexanone in glacial acetic acid under reflux. These intermediates on reaction with substituted aromatic acid chlorides in alkaline media finally converted to N-Substituted tetrahydrocarbazoles. Fifteen compounds are synthesized and charaterized by their melting point (MP), IR, NMR, MS…

This section introduces the background of gene therapy in Parkinson’s Disease, especially on brain cells targeting therapy. It provides the rationale for further proposal of brain cell targeted PD therapy based on Ultrasound-meditated microbubble delivered AAV vector or RNAi. 1.Parkinson’s Disease, a common CNS disorder with no adequate treatment in pharmacological approaches Parkinson's disease (PD) is a progressive, central nervous system (CNS) disorder, belonging to a group of conditions…

After going through today’s lesson, in my opinion, I find that negative feedback mechanism is more important than positive feedback mechanism. Both mechanisms are important to the body, but I feel that negative feedback mechanism is more crucial to the body than positive feedback mechanism. Here is why. The positive feedback mechanism is only used when there is a potentially dangerous situation or a stressful process which must be completed quickly. Moreover, our body only uses the mechanism in…

Ototoxicity may be defined as “damage to the structure and function of the inner ear (auditory, vestibular, or both) that results from exposure to toxins” (Campbell, 2007). Exposure to toxins is often the result of the administration of therapeutic agents or medications for the treatment of other primary diagnoses. These medications fall into several classes including: aminoglycoside antibiotics, antineoplastic drugs, other antibiotics, antimalarial drugs, loop diuretics, and salicylates. To…

Abstract Psoriasis is a chronic auto – immune disease that is believed to be inherited and most common in women. There are seven types of Psoriasis (Plaque Psoriasis, Guttate Psoriasis, Inverse Psoriasis, Pustular Psoriasis, Erythrodemic Psoriasis, Nail Psoriasis and Psoriatic Arthritis), but the most common is Plaque Psoriasis and it affects 4 million people in the United States. It is characterized by raised, inflamed, patchy, red skin covered with white scales that is cause by an excess of…

different forms, shapes & size 2) Blended conducting polymer Polymer obtained by blending a conventional polymer with a conducting polymer by physical or chemical change. 4. COORDINATE CONDUCTING POLYMER When a metal combines with a polydentate ligand then charge transfer complex containing polymer is obtained. They exhibit corrosion characteristics, and are usually in doubtable in most solvents. APPLICATION OF CONDUCTING POLYMER 1. As sensors into clothing. 2. Conducting polymer textiles as…

Results and Discussion 3.1. Block copolymer formation using halogen exchange Normal ATRP of styrene was carried out at 90 °C using SNS as the ligand, Cu-Br as the catalyst, and EBIB as the initiator. The end group of the resulting polystyrene (PS-Br) is a bromine atom. The chain extension of PS-Br as a macroinitiator is usually associated with poor control when MMA monomers are used for the second…

Basic Biology The documents I attached include a lab report, worksheets, notes and one exam. My most memorable experiences in biology were in the lab. I got to test the effectiveness of lactase drops when exposed to solutions containing different pH or temperatures. My results indicated that the lactase enzyme had the optimal catalytic activity at temperatures similar to those found in the human stomach; however, the low pH in the stomach–ranging from 2 to 5– rendered the drops ineffective…

Abstract Angiogenesis is an essential process for organ growth and repair. Thus, an imbalance in this process can lead to several diseases including malignancy. Angiogenesis is a critical step in vascular remodeling, tissue damage and wound healing besides being required for invasive tumor growth and metastasis. Because angiogenesis sets an important point in the control of tumor progression, its inhibition is considered a valuable therapeutic approach for tumor treatment. Chronic liver disease…

General Introduction Dietary lipids: Dietary lipids consist of a broad group of compounds that are soluble in organic solvents and insoluble in water. Their density is lower than water and consistency varies from liquids to solids at normal room temperature, depending on their structure and function. They are also referred as ‘Oils’ which are liquid and ‘fats’ which are solid at room temperature. Lipids are the important constituents of diet due to their higher energy value. One gram of lipid…