Laboratory rat

An editorial in Nature Reviews Drug Discovery describes how “tamoxifen, one of the most effective drugs against certain types of breast cancer”, would have been abandoned because it causes liver tumors in rats (Follow the Yellow Brick Road, 1). This was a problem that did not carry over to humans. The leukemia drug Gleevec was almost lost because it caused severe liver toxicity in dogs- but not in humans. Fortunately, manufacturers persisted with the development…

Imagine you were thrown in a cage, or beaten up for no real reason at all, or even being forced to do something you do not want to do, only to entertain others. This is how millions of animals are being treated today. It is unacceptable for people to do this to other living creatures, and it should be stopped. Over a million animals are abused and killed every year despite the fact that animal cruelty is a felony which can result in jail time of over 15 years and a $500,000 fine. This type…

If a laboratory of bunnies are at stake to find a cure for cancer, I suppose I would be in favor of the experimentation, but because thousands of bunnies are dying so that first-world females can have luscious red lips and sparking eyelids, then I am in against…

using animal testing because of the number of animals that are killed each year, the neglect and abuse that the animals go through and the alternative research methods that can be used. Each year, more than 100 million animals are killed in laboratories for cosmetics testing (Medical Testing). The animals in these labs are abused and treated inhumanely. The animal welfare act was created to help protect these animals. However,…

The experiments are usually flawed in some way and a shocking amount of money has been wasted on them. The US National Institutes of Health spend $14 billion on animal testing each year out of it’s $31 billion budget. Rat “phototoxicity tests” cost about $11,500 while a test excluding animals would cost around $1,300. An “unscheduled DNA synthesis” test using animals cost $32,000. An in vitro test costs less than half that at only $11,000. Some animal tests can cost…

According to the Center for Disease Control’s National Health and Nutrition Education Survey, in 1959, 13% of adult Americans were overweight or obese. In 2010 that figure had climbed to 69.9% (CDC/NHANES, 2011). Obesity, a risk factor for diabetes, heart disease, cancer, and stroke has reached epidemic proportion in the United States. It continues to increase across the population regardless of age, education, or socioeconomic level. In 1972 Michael Jacobson, the director of the American…

disorders or degenerative diseases, which have been shown to be caused by disorder in RyRs (6,7), have also been identified to be caused by exposing to lead (15,16). Further, previous research results in our laboratory indicate that lead exposure affects RyRs both cultured cells (17) and rats level (data is yet unpublished). However, whether there are interactional potential between their molecules is under elucidated and still needed for further…

In the United States, animals are abandoned, beaten, and fighting for their survival every day. Forced to live in unhygienic conditions with no water or food, they don't have very much hope as they live out their days lacking the empathy or consideration that they deserve. Some are discovered and rescued, given the opportunity to experience how magnificent their lives can be; others aren't so fortunate. In order to change as country, we must stick up for these mistreated animal’s rights…

surgeon remains to stand at the forefront of my goals while on my journey to become a medical doctor. This decision is further supported by the work that I conduct in Dr. Cato Laurencin’s laboratory. The internal thrill that pushes through each stroke of my scalpel blade during tissue isolation on cadaver rats makes me know that even though I am starting with animals, I am destined to become a surgeon. The clinical translation aspect of my research further motivates me to consistently put my…

animals is cruel and unfair since these lovable creatures have no choice in the experiment, but most animals used in testings are disposable and are reused so that only one animal is tested on. For instance, 84% rats, mice and other rodents are used in experiments and are all specially bred laboratory species. These rodents are not only reused in experiments but are specifically bred in labs to be tested on, so they were never wild and free in the first…