Ketone

The methoxy groups and the ketone group give the molecule a surface anionic charge which helps in binding to the target site. Indanone ring provides metabolic stability to the compound and so donepezil has a longer half-life. Physical properties: Donepezil is mainly given in its…

Pathophysiology Insulin is made by special cells called beta cells that are produced by the pancreas. Insulin is used to regulate glucose for metabolism. Insulin allows glucose to enter cells and without this glucose would not enter the cells of the body and blood sugar levels would rise in the blood, resulting in hyperglycemia. This process of high sugar in the blood without metabolism will eventually develop into Diabetes Mellitus. There are two types of Diabetes, Type 1 and Type 2. Either…

Diabetes afflicts more than 25.8 million people within the United States, or 8.3% of the population and is rising each year (Klein, 2013). From my personal experience, I see many patients newly diagnosed or hospitalized due to complications from diabetes. With diabetes on the rise in the US population, management, and patient education is something that needs to be more prevalent. Through better patient education and teaching, a number of hospitalizations in regards to diabetic side effects can…

Abstract 6- bromo-2-(4-chlorophenyl)quinazolin-4(3H)-one derivatives 2-7 were synthesized.. The synthesized compounds were evaluated for their anti-microbial activity using the agar diffusion technique . The tested compounds were evaluated against, Gram +ve bacteria , Gram -ve bacteria, Yeast and Filamentous Fungus. Minimum inhibitory concentration (MIC) was made in vitro for compounds which showed antimicrobial activity. Compound 3b has broad spectrum activity against Gram +ve bacteria, Gram…

Diabetes Mellitus Thousands of people around the world suffer from a disease called type one diabetes mellitus that can cause them severe consequences if its not treated in time. These disease has impacted millions of people worldwide and the number in millions is increasing rapidly as the years go by. The lack of exercise and a health diet is a prior factor to prevent these disease so you dont have to go through the symptoms and consequences of these disease. People with this type of diabetes…

In pursuit of our continued interest in the development of solvent-free and green synthetic procedures, we decided to explore the use of tartaric acid catalyst for synthesis of polysubstituted quinolines via Friedlander condensation in high to excellent yields at 70 °C under solvent-free conditions. Initially the reaction between 2-aminobenzophenone (1.0 mmol) and dimedone (1.0 mmol), as the model reaction was examined in the presence varying amount of tartaric acid as catalyst and the results…

belongs to a Zingiberaceae family including cardamom and turmeric that are mostly cultivated in tropical areas.1(p373) The primary component of ginger called gingerol comes from the root of the plant and its spicy aroma mainly due to the present of ketones called gingerols.1(p132,),2 Ginger is widely consumed in diet as a flavor in cooking and commonly used to treat nausea and vomiting during pregnancy in traditional Chinese medicine.3 Ginger preparation has been mostly used in Asia since the…

The separation of mixtures to obtain pure products is done through a technique called distillation. This lab looks at two different distillation techniques, simple and fractional. Acetone and butanone were mixed together and then put through the distillation process in order to obtain each as a pure substance. These substances were boiled into vials that gave us fractions #1-4. Fraction #1 was obtained through simple distillation and fractions #2-4 were obtained through fractional distillation.…

substances found in the repair workshops Fuel Antiknock Agents An antiknock agent is a fuel additive which increases the fuel combustibility and reduces engine knock. Antiknock agents are usually made up of methylpentadienyl manganese tricarbonyl (MMT) or ketone solvents like methyl isobutyl keton. These ingredients may lead to eye irritation, dizziness, breathing problems, nausea and headaches. Long-term exposure to MMT damages the kidneys and liver. Manganese is a neurotoxin which may be…

Diabetes and Exercise Diabetes mellitus is a common, chronic disease in which a person’s blood sugar (glucose) levels are often too high. Getting exercise on a regular basis is an important part of diabetes treatment. WHY SHOULD I EXERCISE REGULARLY IF I HAVE DIABETES? Exercising regularly provides many benefits for people who have diabetes. Some of these benefits include: • Lowering your blood glucose level. During exercise, muscles use glucose in your bloodstream for energy. This causes…