1. INTRODUCTION The French paradox describes the lowered incidences of coronary heart diseases (CHD) in French people with respect to their diet which consists of high amounts of saturated fats. It is one of the many paradoxes with examples such as the Israeli paradox, which shows that although having a diet low in saturated fats, the Israeli Jews have increased incidences of CHD . This paradoxical event caused elevated interest in the causative factor that can seemingly lower the incidences of…
OBJECTIVE: To deliver lornoxicam into systemic circulation by engineering ethosomal gel formulation. RATIONAL OF WORK: Because of their improved pervasion of medication through skin. lornoxicam is BCS class II medication causes gastric bothering when managed orally ethosomes are stages for the conveyance of vast and differing gathering of medications. due to their generally safe profile. better understanding agreeability can be utilized as a part of the manifestation of gel,…
SEARCH FOR AN H2-RECEPTOR HISTAMINE ANTAGONIST In the beginning of the 20th century, Histamine was discovered. Subsequent studies proved that histamine was the principal mediator of the inflammation and the shock. Antihistamines were used by the pharmacologists to identify various actions of the histamine in the different tissues. Several actions of histamine had been noted that could not be specifically antagonized by these drugs: for example, the stimulation of the gastric acid secretion in…
Physical Properties of Carbohydrates Steroisomerism - Compound shaping same structural formula but they differ in spatial arrangement. Example: Glucose has two isomers with respect to penultimate carbon atom. They are D-glucose and L-glucose. Optical Activity - It is the rotation of plane polarized light forming (+) glucose and (-) glucose. Diastereo isomeers - It the configurational changes considered C2, C3,…
Potassium Permanganate Test: 1. Three drops of the compound to be tested are dissolved in 2 ml of water or aqueous ethanol. 2% KMnO4 solution (a purple solution) is added drop wise and the solution is shaken. 2. The purple color of the KMnO4 solution disappears and a precipitate of MnO2 is formed. A negative test is if there no precipitate. 3. Repeat for every unknown and record observations. Observations and Results Water Solubility Test: When the test was conducted and observations were made,…
The operating pressure is 0.3kg/cm2 and 4.3 kg/cm2 in the second column. All isomers of xylene was recovered from the column and were collected. The results obtained were 97 mole% benzene, 96 mole% toluene and 98 mole% xylene. In this process separation of acetonitrile from waste solvent acetonitrile is carried out. The impurity…
Pyrogallol absorbed 0.146 of light and produced the most benzoquinone. Structure determines function (Reece et al., 2014). Though hydroquinone an isomer of catechol, the structure of hydroquinone places the hydroxyl groups at opposite end of the six carbon ring. The structure of benzoquinone has two double bonds with oxygen placed next to each other. The structure of pyrogallol has three hydroxyl…
Oligosaccharide structures are strongly associated with their potential biological activities. Despite the biological activities of oligosaccharides have known for years, the lack of structural details limits the study of their potential applications. A rapid and effective method for identifying oligosaccharides is desirable yet the complete structural characterization of novel oligosaccharides remains challenging. The high polarity nature and highly branching, isomeric structures makes…
Results and Discussions Table 1: Phytochemical analysis of turmeric and apple peels extracts Phytochemical analysis Turmeric Extracts apple peel extract Total Phenolic(mg/g)content 93.30 ±0.03 82.52±0.013 Total flavonoid content (mg/g) 43.6±0.3 33.43 ± 0.06 Tannin (mg/100 g) 91.08±0.72 77.40+0.36 Reducing power (μg/ml) 25±1.7 21±5.5 Alkaloid (mg/100 g) 0.76±0.01 13.60+0.51 The Phytochemical composition of turmeric extract and apple peel extract are illustrated in table (1). Both are rich in…
Salbutamol Discovery Chiral chemistry was introduced in 1848 by French chemist and biologist, Louis Pasteur. He discovered this new branch of chemistry after he separated two isomers of ammonium tartate (1). This paved the way for several progressions in the pharmaceutical industry. Although it took approximately a century for scientists to use chiral compounds as effective drugs, they have played a remarkable role in the life of plants and animals (1). The credit for discovering the chiral…