Islets of Langerhans

The Endocrine System controls bodily functions that tend to occur over a long time. Taking a similar role to the nervous system to keep the body in a state of homeostasis. Through the use of a negative feedback loop the Endocrine system insures the proper amount of hormone is in the body at any given time. These hormones serve functions from growth to balancing ion levels in the body. The Endocrine system is specifically down to the hormone meant for homeostasis. The Endocrine System is…

the nerves, the heart, and the blood vessels. T1DM is defined as a chronic disease characterized by hyperglycemia as a result of inadequate production of insulin by the pancreas. This occurs due to autoimmune destruction of the β cells in the islets of Langerhans (10) which is triggered in genetically susceptible individuals by environmental factors.(11) Maintaining an appropriate glycemic control is important to prevent long term complications of…

Stem cells are characterized by the ability to replicate themselves limitlessly. After being created, these identical copies can remain undifferentiated for a long period of time. When receiving specific signals from internal and external environments, they transform themselves to a particular type of cell in the body with specialized functions and features. Therefore, they act as an essential system for tissue repair and growth (National Institutes of Health, 2009). Based on their origins, stem…

blood-glucose levels is paramount for survival. The pancreas is a small organ located below the stomach it has a number of functions. One of the most important is the regulation of blood-sugar levels. The pancreas contains special cells known as the Islets of Langerhans that detect blood-glucose levels. Kidneys:Kidneys regulate the amount of water present in the human…

Germany) (International Diabetes Federation, as cited by Lewis et al., 2014). The disease result from progressive destruction of beta cells in the pancreas due to autoimmune processes in susceptible people. In these individuals, autoantibodies to the islet cells may cause a reduction of 80-90% of the normal beta cell function before hyperglycemia and other clinical manifestations may occur. Genetics and viral exposure are predisposing factors believed to contribute to the cause of type 1…

Introduction The topic for the Evidence Based Practice Proposal is Type 1 Diabetes. I want to know what interventions can be provided such as education that will encourage patients with this disease to maintain better control of blood glucose levels. A hemoglobin A1c level is an indicator of how well controlled the patients’ blood sugar levels are, and how well they manage their diabetes over the course of three to four months. The hemoglobin A1c test is checked by having blood drawn or by using…

Introduction: The purpose of this study is to determine if obesity in pregnant women leads to higher rates of obesity in their offspring. According to the World Health Organization, obesity should be treated as a world wide epidemic ( WHO). One in three Americans are obese and many more are overweight, or on the borderline of obesity. Public opinion of obesity has always been that is is simply due to lifestyle choices or poor diet and exercise; however, the World Health Organization believes…

Problem People with diabetes who cannot make their own insulin. Making synthetic insulin for these patients due to allergic reactions from animal insulin such as from pigs. Introduction The pancreas produces several hormones which balance the sugar (glucose) and salt levels inside the body. One of these hormones produced by specialized cells (beta cells) is called insulin (a small protein). Insulin aids in the transport of glucose into the cells for use of energy. When too much glucose…

After going through today’s lesson, in my opinion, I find that negative feedback mechanism is more important than positive feedback mechanism. Both mechanisms are important to the body, but I feel that negative feedback mechanism is more crucial to the body than positive feedback mechanism. Here is why. The positive feedback mechanism is only used when there is a potentially dangerous situation or a stressful process which must be completed quickly. Moreover, our body only uses the mechanism in…

catalysed by the transmembrane protein, adenylate cyclase, initiated by the release of GTP-bound α subunit. This increases the cytosolic levels of cAMP which then activates protein kinase A. This successively phosphorylates glycogen phosphorylase b stored in the cell, as phosphorylase kinase is initiated. Phosphorylation of glycogen phosphorylase b converts to phosphorylase a. This enzyme releases glucose-1-phosphate from glycogen polymers. After this the phosphate group is moved from the C-1…