Islets of Langerhans

Part two High blood glucose levels. When blood sugar levels rises, like after a meal, insulin is secreted by the beta cells in the islets of Langerhans in primary response to decrease the blood concentration of glucose. As seen in diagram 2. The beta cells act as the receptor and the control. The beta cells detect a rise in glucose and in response secretes insulin. The islets of Langerhans do not depend on the nervous system for their output of insulin. As a result the beta cells respond directly to blood glucose levels. When there is a rise in blood glucose, glucose is transported into the beta cell by facilitated diffusion through a glucose transporter. Elevated concentrations of glucose within the beta cells leads to membrane depolarization…

The islets of Langerhans enable the blood glucose level to be finely controlled. When blood glucose rises more insulin is released which stimulates body cells to absorb glucose, glucagon secretion also falls. Liver and muscle cells convert the glucose to glycogen for storage and other cells in the connective tissue called adipose cells convert glucose into fat. The opposite occurs when blood glucose rises, more glucagon is released from the liver and less insulin is secreted. Glucagon stimulates…

“182, DAPI – 18, glucagon – 24, insulin.” My heart sank as I entered more values from the second set of data. It was increasingly obvious that there was no discernible difference between the two sets of cells. My first independent task as a member of the University of Alberta Diabetes Institute was to review hundreds of cell images. The cells came from the human pancreas—the Islets of Langerhans—a medieval sounding name that seemed contradictory to their mundanity under a microscope. My task…

sugar regulation is the process by which the levels of blood sugar, primarily glucose, are maintained by the body within a narrow range. This phenomenon of tight regulation is commonly referred to as glucose homeostasis. Insulin and glucagon are the most well-known of the hormones involved. Blood sugar levels are regulated by negative feedback in order to keep the body in homeostasis. The levels of glucose in the blood are monitored by many tissues, but the cells in the pancreas's Islets of…

This retrospective histological and immunohistochemical study was designed to evaluate the pathogenesis of pancreatic toxicity induced by patulin exposure and the role of goji extract to eliminate its toxicity. It has been reported that the relationship of the endocrine–exocrine parts of the pancreas is a complex one because of the close anatomical and functional links. The impairment of the endocrine part of the pancreas has a marked effect upon its exocrine component. It was stated that islet…

Eugenia Winfred Matukeni 102283 ILSC003 Assessment A Why is insulin used and how does it work in the body? In simple terms insulin is a substance produced by the body and is used to turn sugar into energy. In scientific terms it is a 51-amino-acid polypeptide hormone composed of two chains A and B connected by a disulphide bridges(Ahmad 2013). The A chain consists of 21 amino acids and the B chain has 30 amino acids. The hormone insulin is secreted by the beta cells of the islets of Langerhans…

with the pancreas; specifically the Islets within the pancreas or the Islets of Langerhans. The islets contain several types of cells including alpha cells and beta cells which regulate the body’s blood glucose levels through the release of glucagon and insulin, respectively. In type I diabetes, the body is unable to produce insulin due to a lack of functional beta cells - the body assumes the beta cells are foreign invaders, so the immune system attacks and destroys the cells,…

create the response to the internal change and to cause the system to counteract it and help keep constant. Blood glucose regulation is a type of homeostasis and therefore uses negative feedback, receptors, a control centre and an effector to keep blood glucose levels in the body stable. In blood glucose regulation the receptors are the alpha and beta cells which are found in the control centre which is the Islets of Langerhans and the effector is the liver. The islets of Langerhans are a…

The pancreas Is both an exocrine and an endocrine gland. The endocrine tissue takes the form of one to two million tiny clusters of pancreatic cells called islets of Langerhans. The two hormones insulin and glucagon are secreted by the islet of Langerhans. The islet of Langerhans contains the alpha and beta cells. The Alpha and Beta cells detect the change in the blood glucose. The pancreas is adjacent to the gut and on the portal vein which drains nutrient from gut to the liver which means that…

Adrenal medulla:- The adrenal medulla produces the hormones epinephrine and norepinephrine under stimulation by the sympathetic division of the autonomic nervous system. Both of these hormones help to increase the flow of blood to the brain and muscles to improve the “fight-or-flight” response to stress. These hormones also work to increase heart rate, breathing rate, breathing rate, and blood pressure while decreasing the flow of blood to and function of organs that are not involved in…