Ischemia

Pressure ulcers have become more prevalent among patients in any health care setting. The development of pressure ulcers have many factors that contribute to the development which makes it difficult to know what exactly caused the pressure ulcer to occur. With many factors that can be involved the treatment process can take some time to see what will work for each patient as well as the stage the pressure ulcer is in. The further developed a pressure ulcer the longer it takes to heal, the…

the blood through patent blood vessels to supply the tissues throughout the body. Impaired perfusion may occur when the blood supply is reduced or completely interrupted (Giddens, 2013, p. 148). A term that represents this is known as ischemia. An example of ischemia would be when blood supply from the coronary artery to the myocardium is reduced it is known as myocardial…

1. Coronary perfusion is a crucial factor in meeting cellular oxygen demands, which of the following factor can cause the decline in coronary perfusion? a) Heart Rate b) Contractility c) High blood pressure d) Platelet aggregation and thrombosis Answer: D Answer Rationale: A. (Incorrect) Heart rate and coronary perfusion is not correlated. An increase or decrease in heart rate along does not necessarily impact the coronary perfusion. In most cases, it is the vasodilation and vasoconstriction…

to troponin levels and the patients were treated according to the recommendations of the international guidelines. The patients were discharged with indication of stress echocardiography with exercise or dobutamine to rule out induced myocardial ischemia. This functional test was not performed if the attending physician preferred to order a conventional or computed tomography coronary angiography. This hypothesis-generating observational study enrolled 100 consecutive…

in urine) [2]. As the metabolic precursor of uric acid, xanthine is the first indicator of an abnormal purine profile and can serve as a marker of many diseases including hyperuricemia[3], gout[4], xanthinuria[5], perinatal asphyxia[6], cerebral ischemia[7], tumor hyperthermia[8] and pre-eclampsia[9]. Uric acid is typically present at serum concentrations of ∼200−400 μM and is by far the dominant purine of this class in biological fluids [10-15]. Hypoxanthine is the precursor to xanthine and is…

syndrome, also called Wallenberg syndrome and posterior inferior cerebellar artery syndrome, is a disease that presents with a constellation of neurologic symptoms due to injury to the lateral part of the medulla in the brain, resulting in tissue ischemia and necrosis, typically from blood clot (stroke) impeding the vertebral artery and/or the posterior inferior…

Persons who present in any healthcare setting with a complaint of chest pain should be evaluated for the presence of signs and symptoms of ACS. Appropriate assessment measures include vital signs and a 12-lead ECG to assess for changes suspicious for ischemia or infarct. Patient E was chest pain free on arrival, his ECG did not show any acute ischemic changes, and his vital signs were stable. Further assessment by the healthcare provider is indicated. The physician questioned Patient E about his…

Traditional Chinese Medicine pharmacology. In Dr. Junping Kou's lab, my teammate and I finished two research projects, my contribution to these projects including acquiring the funding, creating the mouse model of acute hypoxia-induced organs injury and ischemia-reperfusion injury, performing Western Blotting to measure protein expression level, providing evidence for the potential clinical application of Diosgenin. In my last year in undergraduate, I joined Dr. Haiyan Chen's lab, we synthesized…

Pathophysiology Assignment Binswanger's disease: Binswanger’s disease is one of the diseases that could affect brain’s functions, Binswanger's disease, also called subcortical vascular dementia, caused by microscopic areas of damage to the deep layers of white matter in the brain. The damage is the result of narrowing of arteries that feed the brain¹. People who have hypertension, diabetes, some heart diseases and smoke are luckily to have this disease. The symptoms of the disease are short…

Necrosis occurs as a result of external injury due to cellular injury, bacterial toxin or trauma to a particular area of the body. Necrosis differs from apoptosis in a couple of ways. First, the morphological changes that a cell undergoes are different in necrosis compared to apoptosis. Secondly, apoptosis is highly regulated, however, necrosis is unregulated. The morphological changes that a cell undergoes during necrosis are the swelling of the cytoplasm, irreversible damage to the plasma…