Insulin resistance

constant level of drug over a 24-hour period. Within the class of calcium channel blockers, nifedipine belongs to the dihydropyridine variety. 2. Dihydropyridines have a profound effect on the vascular tone by causing a decreased peripheral vascular resistance resulting in hypotension. In mild cases of overdose, a decrease in both systolic and diastolic blood pressure causes hypotension but the heart is spared due…

A sample of 59 obese girls with PCOS aged 12-19 years of age, 26 girls who reduced their weight after 1 year, decreased cFT, insulin concentrations, and homeostatic model assessment, and increased SHBG concentrations. The main challenge is to maintain the weight loss. Pharmacological treatment is another option to reduce PCOS symptoms. Oral contraceptives and insulin sensitizers are effective for adolescents with PCOS in combination of lifestyle intervention or when lifestyle intervention…

is a disease where sugar levels increase drastically due to the lack of insulin production or incorrect response, which usually converts glucose into energy. Diabetes affects multiple organ systems, including the digestive system, endocrine, immune, muscular/skeletal, nervous, and excretory. During digestion, when food enters the first part of the small intestine, the pancreas is in charge of releasing enzymes, such as insulin, to assist in digesting the fat, protein, and carbohydrates present.…

produce insulin. In a cell, there is a special protein, called a receptor, that binds to insulin.The pancreas is responsible for producing insulin. The insulin must bind to the cell in order for glucose to then be moved in and metabolized. In addition to being used to metabolize glucose, insulin also inhibits the release of glucose and other substances from the liver and helps make protein in the body…

Microneedles Insulin is most effectively taken through direct injection, which is most typically done through a needle. Traditional needles are bulky and are oftentimes associated with pain. Microneedles are much smaller in dimensions, making them able to effectively release insulin into the body while not reaching nerve cells which would cause pain and discomfort. Microneedles are designed to puncture only the top 20–50 μm of the skin, because the stratum corneum, which is the outer layer…

Diabetes type 2 is a chronic condition in which insulin does not respond to high glucose levels in the blood. The insulin produced in the body has a resistance to the glucose. The pancreas may still produce insulin, but the insulin does not have the usual effect on cells. Diabetes affects people when there are high blood glucose levels, which lead to damage of blood vessels. This can lead to several complications including heart disease, kidney damage, nerve damage, eye damage and can cause…

Diabetes mellitus (DM) is one of the leading chronic, lifelong condition worldwide. DM can cause high rates of morbidity and mortality due to complications associated with the disorder. DM is characterized by hyperglycemia due to a lack of insulin, insulin resistance, or can be consisted of both. The four main types of diabetes mellitus include type 1 diabetes mellitus, type 2 diabetes mellitus, gestational diabetes mellitus, and other specific types (Darby, 2015, 824). A high rate of…

disease is when the body sees normal parts of itself as foreign substances and tries to kill it (Diabetes Mellitus). The insulin is contained in beta cells in the pancreas. Insulin helps our body use sugar which is why Type 1 Diabetes occurs when these cells cease to exist (Diabetes Mellitus). Due to Type 1 Diabetes being a autoimmune disease, the beta cells that make insulin are attacked by white blood cells unknowingly. The body is not energized in the day due to the loss of these cells…

while it is growing so those hormones do not allow the action of working the insulin in the mother’s body. As this result the mother need much as twice insulin in her body while she is pregnant. This disease do not affect the children’s body because it start to develop after the child is formed. Above 9% of pregnant women contract gestational diabetes. Type 1 is a serious condition in which the pancreas make enough or no insulin. It only affect in children and teenager. Type 1 and type 2…

1. The 48 years old Native American women presenting to the Indian Hospital is taking Lisinopril because of hypertension as one of the conditions documented in her past medical history. Hypertension is supported by the current measurements of the blood pressure readings of 165/100. Lisinopril is an angiotensin –converting enzyme inhibitor (ACE) considered as one of the first line treatment option for hypertension. The pharmacological mechanism of action for Lisinopril is to inhibit the action…