Indicator

Acid Base Balance Study Guide Definition: The body’s ability to regulate and compensate for variances of the acidity or alkalinity of body fluids through mechanisms in the brain, kidneys, lungs, and buffering system. Concept Key Terms: • Acid: any substance that has a pH less than 7.0 • Acidosis: the condition of having too much acid build up in body fluids, below 7.35 • Alkalosis: the condition of having too much alkaline build up in body fluids, above 7.45 • Anion: a negatively charge…

Uranium and its decay products can be found in the environment through a wide array of anthropogenic activities such as mining, nuclear and power generation industries and the production of phosphate fertilizers .(Sprynskyy et al. 2011) They pose a severe, long term ecological and public health threat (Khani 2011, Landa 2003) and therefore there is a considerable effort in the removal of these pollutants before their final discharge in the environment, as well as their recovery as an energy…

PRE FORMULATION STUDY: Pre formulation testing was an investigation of physical and chemical properties of a drug substance alone and when combined with excipients. It was the first step in the rational development of dosage forms. Class: -Pre formulation study can divide into two subclasses: API characterization, Compatibility study Active pharmaceutical ingredient (API) characterization:- Organoleptic evaluation:-These are preliminary characteristics of any substance which is useful in…

In this lab we wanted to identify what the four mystery liquids were using density and their characteristic properties. We were initially given four liquids that were labelled numbers 1- 4, some graduated cylinders, and a scale, but we also knew that the 4 liquids were ethanol, vegetable oil, water, and cyclohexane. Using the mass that we found when we measured the liquid and using only 10 mL of the liquids we were able to calculate the density and easily identify the liquids and see if they…

Malachite Green Assay: The reaction that AGPase catalyzes produces PPi. The resulting PPi that is produced is hydrolyzed by an inorganic pyrophosphatase (Sigma Aldrich) to generate phosphate (Pi). Each reaction for the assay was conducted on a 96 well plate and the reaction mixture was 50µL and contained Pre-Mix which contained 50mM HEPPS, pH=8.0 (MP Biomedicals), 10mM MgCl2, 1.5mM FBP (Sigma Aldrich), and 0.2mg/mL Bovine Serum Albumin (Sigma Aldrich), and 1.5mU/µL yeast inorganic…

Conclusion: I predicted that liquid A was glycerine due to a calculated density of 1.38 g/mL. However I was wrong the actual density of liquid A was 1.38 g/mL and the substance was actually corn syrup. Therefore the percent of error for the density of liquid is 1%. For liquid B I had predicted that its substance would be Glycerine due to the calculated density of 1.19 g/mL. I was incorrect for the density of liquid B which was actually 1.26 g/mL, but because the calculated and actual densities…

The two main purposes of the lab were to determine the percent by mass of acetic acid in vinegar and to determine the molar concentration of a strong acid. In both parts of the experiment a volumetric analysis was used. This is primarily the aid of volumetric glassware in order to determine specific measurements and calculations. Potassium hydrogen phthalate was used as the primary acid standard to determine the molar concentration of the sodium hydroxide solution in part one of the experiment.…

The objective of the lab was to determine the densities of known and unknown metal solids and liquids. For the liquids, initially, an Electronic Scale was placed onto Work Bench, and it was zeroed. An empty 50 mL Graduated Cylinder was placed onto the scale, weighing 54.00 grams. In increments of 10 mL. Until the volume was 30.00 Ml, 10.00 mL of water was poured into the Graduated Cylinder. In between each increase of 10.00 mL, the total volume and mass were recorded. For the known metals, the…

NIMOTOP INJECTION Nimodipine 0.02% solution contains the following excipients: Ethanol 96%, Macrogol 400, sodium citrate, citric acid, Water for Injections Ph. Eur. These excipients consist of properties that aim towards the proper functionality of Nimotop. They consist of inherent stabilities that cause little or no effect in the stability of the drug and they do not have any acute or chronic toxicity. The excipients are also added into the Nimodipine 0.02% solution to enhance the biological…

To determine optimal pH value for the hydrolysis of p-NPG by leukocyte GCase, we examined effects of variable pH (4.0-5.5) at a constant substrate concentration (5mM). Figure 1 shows the pH activity curves of leukocyte GCase assayed in the presence and absence of 6 mg per ml Sodium taurocholate. In the absence of the pure sodium taurocholate, the activity in the range of pH 4.0-4.8 was considerably lower. However, in the presence of pure Sodium taurocholate, leukocyte GCase was optimally active…