In vivo

such as depressive symptoms, suicidal ideation, disruptions in relationships, sexual problems, and shame associated with the assault. The exposure component consists primarily of prolonged, repeated exposure to the traumatic memory and repeated in vivo exposure to trauma-related feared situations that the survivor avoids. The therapeutic goal is to activate trauma-related fear and modify the pathological elements that are thought to maintain PTSD symptoms. Doing so helps the survivor reduce…

therapy and cisplatin (one of the most common chemotherapy drugs) based (DDP) chemotherapy. After tests with nude mice bearing human small-cell lung cancer, data showed that AdVPTEN in combination with DDP chemotherapy repressed NCI-H446 tumor growth in vivo. In this study, it was also concluded that AdVPTEN gene therapy plus DDP chemotherapy reduced the microvessel density (MVD) of NCI-H446 tumors in human small-cell lung cancer. Chemotherapy remains the main procedure in the treatment of…

C5086 Description: IC50: 100 nM, 12 and 60 µM for nNOS, eNOS, and iNOS, respectively Vinyl-L-NIO is a potent and selective inhibitor of nNOS. Nitric oxide synthase (NOS) catalyzes the NADPH- and O2-dependent conversion of L-arginine to nitric oxide (NO) and citrulline. Three isoforms including the neuronal (nNOS), endothelial, and inducible have currently been identified. Since NO overproduction is able to contribute to various pathophysiological conditions, NOS inhibitors are considered as…

Although environmental and genetic factors are prevalent, a strong belief in transmission of an anxiety disorder is within the family. According to Fisak and Grills Taquechel (2007), a child’s parents can contribute to the likelihood of developing anxiety through modeling of learning experiences, transferring of information, and reinforcement schedules. A top-down or bottom-up approach can be used to predict the source of the phobia or fear. Visual signs of fear, such as facial expressions, in…

I believe that there is nothing wrong with eating meat because it has developed humans for millions of years and is also a natural occurring process. However, I do believe that the method of which we obtain our meat including factory farming is unethical and needs to be changed. The amount of respect that humans have for the animals we eat is miniscule, and it needs to be fixed. Similar to Pollan’s viewpoint on meat-eating and the process of obtaining meat, I believe that animal experimentation…

1. Undergraduate Research: I was an undergraduate research assistant in different labs, including biomedical engineering and Traditional Chinese Medicine pharmacology. In Dr. Junping Kou's lab, my teammate and I finished two research projects, my contribution to these projects including acquiring the funding, creating the mouse model of acute hypoxia-induced organs injury and ischemia-reperfusion injury, performing Western Blotting to measure protein expression level, providing evidence for the…

Gene therapy consists of repairing abnormal genes which leads to disease. In the treatment of genetic maladies, drug genes are introduced into the diseased cells. These genes are the healthy genes that must replace the defective genes that are responsible for diseases. They are introduced into the disease cells using the vectors. Vectors are the safest means of transport from the healthy gene to the disease cells; This vector must contain the gene and be capable of conveying it and bringing it…

3. Preparation of microemulsion:- Microemulsion was prepared by dispersing required quantity of Aripiprazole (15 mg/ml) in appropriate quantity of oil. The mixture was homogenized and to it, accurately weighed quantity of surfactant: cosurfactant blends was added in small portion with stirring. The blends were mixed thoroughly using magnetic stirrer and to it add dropwise double distilled water with continuous stirring around 10 min. compositions of ARP microemulsion shows in Table 1. 4.…

Furthermore, Latino media in America also has a strong influence over how populations are perceived in a society. In “Closing the Telenovela’s Borders: Vivo por Elena’s Tidy Nation,” scholar Adriana Estill analyses Latino telenovelas as a platform where “nationality, nationalism, and Nation are produced and reproduced” (Estill 75). Through government involvement and censorship, telenovelas can create “an ideal space where the ideal citizen is constructed and disseminated” (Estill 85). Racial…

The human body is made up of a variety of cells, tissues, organs and an organ system. Diseases can affect any component of this structural hierarchy. Diseases that affect certain tissues such as cartilage and bones are largely responsible for the pain and immobility many humans can suffer from. Osteoarthritis, a cartilage disease, is the most common form of arthritis. It can affect any joint in the human body, such as the hip, knee, spine, and joints in the fingers. Osteoarthritis results in the…