Hemophilia Hemophilia is a bleeding disorder in which blood doesn’t clot normally and results in excessive bleeding. The Jews were the first to recognize hemophilia and was described in the Talmud, which is a collection of Jewish writings, and stated that if two brothers had died after getting circumcised the next male baby from that family didn’t have to go through the procedure. Years later in 1803 a physician named Dr. John Conrad Otto in Philadelphia discovered that the disease was…
Physical education curriculum provides an indispensable opportunity in the establishment of physical literacy, however the aim of PL is to move beyond specific proficiency in specific activities to inclusiveness of all abilities and focuses on competencies in a variety of movements and environments. The internationally accepted definition of PL is “the motivation, confidence, physical competence, knowledge and understanding to value and take responsibility for engagement in physical activities…
Introduction The predominant disease that mutant FGFR3 (fibroblast growth factor receptor 3) gene causes is Achondroplasia. Furthermore, Achondroplasia means the absence of chondrocyte formation in bones. Additionally, the transformation of chondrocytes into bone cells is prevalent in the limbs as well as the facial bones of humans (1). Therefore, the predominant symptom of Achondroplasia is bone growth retardation and is found in the limbs as well as facial bones. The majority of people…
This guidance is part of the Administration’s attempt to bring up to date federal agency implementation of NEPA to improve the involvement of the public, transparency, and efficiency of environmental reviews. Under NEPA, a Programmatic Environmental Impact Statement (PEIS) is created for an extensive federal action, such as the adoption of a plan, policy, program, or regulation. 40 C.F.R. 1502.4(b). Often referred to as a “strategic environmental assessment” by NEPA professionals, the…
One environmental issues posted on the Facebook group on Ecologically Conscious Social is climate change’s effect impacts on the Great Barrier Reef where is one of the UNESCO world heritage sites. The Great Barrier Reef is located in Queensland, state of Australia. A concern raised by a group of environmentalists over a threat to the Great Barrier Reef is carbon dioxide (CO2) emissions that emit from burning of coal. The federation government environment minister, Mr. Greg Hunt approved a 16.5…
have small impacts, and therefore, are of little concern. For instance, air quality falls well within regulations(5). And other VECs, migratory birds and terrestrial species, also have modest impacts due to the limited footprint of the project and the wetland compensation proposed as mitigation(5). However, some VECs are more concerning. Three have issues with baseline data: freshwater fish habitat, shellfish pollution harming human health, and marine mammal habitat(5). While the impacts are…
Each of these elements can provide insight in the lack of support for homosexuals as it is not something one is born with but rather learned. Two studies, Lingiardi et. al. (2016) & Village and Francis (2008) examine a number of these different factors that aid in predicting homonegativity, including two that provide strong evidence for homonegativity, religion and personality. Both religion and personality have rather broad definitions and luckily the two studies view them in similar ways.…
curtailed by the drug. MMPs are endopeptidases that degrade proteins of the ECM, and TIMP are their inhibitors. As expected, treatment enhanced the expression of pro-MMP-2 protein and repressed the expression of the TIMP-2 protein. Transforming growth factor-beta (TGF-beta) is a stimulator of collagen production and upregulates collagens in IPF. Nintedanib inhibited TGF-beta-induced secretion of collagens. Through these mechanisms, nintedanib promotes anti-fibrosis and slows the process of the…
environment” (Wechsler, 1958). Wechsler, often referred to the elements in his research as the “non-intellective” as well as the “intellective elements,” which was explained and well-defined in his research as the affective, personal, and social factors (Wechsler, 1940). With the continuation of his research, in 1943, Wechsler’s main question states, “whether the non-intellective, that is affective…
the Nebraska government to reroute the pipeline. 2.1 Environmental Impact Study and Perryman Study As to compile with the National Environmental Policy Act and the Department of State for a presidential permit that included a national interest determination, TransCanada had to prepare an EIS, which was a three-year study and examined “project design and safety, including the potential for oil spills, the potential impact on the Ogallala Aquifer and groundwater in the Sandhills regions,…