Hypoxia

This hypoxia causes periventricular white matter damage, in most cases periventricular leukomalacia (PVL), which affects the white matter around the lateral ventricles; children with these impairments tend to have visual impairments as well as functional motor…

Wuertz et al. (2014) discovered that low nutrients and hypoxia on rat BM-MSCs induces ACAN and COL1 expression and increased proliferation. However, hypoxia leads to the production of lactic acid which results in an acidic pH in the disc. Both hypoxia and high osmolarity typical of the degenerate NP environment were shown to affect discogenic differentiation negatively by decreasing ECM matrix expression…

1. What clinical findings are likely in R.S. as a consequence of his COPD B? There are multiple types of chronic obstructive pulmonary disease (COPD), COPD “characterized by chronic and recurrent obstruction of airflow in the pulmonary airways (Porth & Matfin, 2009). The recurrent obstruction makes it difficult for a person to breath overtime this problem occurs in the lower respiratory tract. COPD compromises the flow of air in the lungs this causes less oxygen that is being circulated…

The development of chronic cough due to reactive airway disease with acute bronchitis can cause discomfort and sleep loss. More so, the person become vulnerable to superinfection, hence, develops activity intolerance and hypoxia. Pneumonia on the other hand can cause dyspnea, chest pain, and anxiety. Though not common, acute respiratory failure and sepsis may happen (Buttaro et al., 2013). The American Lung Association, ALA (2015) indicates that, during treatment of acute…

excess is higher than the normal range, which suggests a metabolic cause. An elevated lactate indicates lactic acidosis as a result of tissue hypoxia as evidence by decreased in systemic blood flows (Ringdal & Gullick, 2015). Therefore, the patient has metabolic acidosis due to an injury to the myocardium that caused a decreased in cardiac output, tissue hypoxia, and low bicarbonate due to rise in lactic acid Also, it is uncompensated as per the PaCO2 is normal (Gandhi & Akholkar,…

Perfusion is a vital component to our everyday living. The definition of perfusion is the process of the body delivering blood to a capillary bed in its biological tissue (Merriam-Webster, 2015). This process helps our blood that caries oxygen get to our vital organs in the body, such as, the brain, lungs, and to our extremities. When our perfusion is compromised however, our blood cannot complete its task and get the oxygen to the parts of our body that need it. If the body does not have a key…

Q1) State the normal values for the partial pressure of O2 at sea level (with barometric pressure of 760 mmHg) in the following a. Inspired air b. Alveolar air c. Arterial blood d. Venous blood 1a- 149mmHg 1b-100-104 PaO2(mmHg) 1c-95-100mmHg 1d-40-50 mmHg Q2) Interpret the probable underlying cause when a person becomes unconscious and dies on exposure to an atmospheric pressure of 200 mmHg. When the human body is suddenly exposed to this pressure…

The primary survey carried out in ED for Mrs. Kelly included assessment of the airway, breathing, circulation, disability, exposure, fluids, and glucose levels (utilization of A-G assessment format). The assessment of the airway showed no signs of obstruction or noisy breathing and the patient was breathing spontaneously, able to talk in full sentences. The airway assessment is done to ensure that airway is patent (Jarvis, 2012). Mrs. Kelly’s airway was open and this assessment is usually…

BILIRUBIN Bilirubin is an orange -yellow substance which is made during the breaking down of RBC’s. It is excreted out of the body through liver. The test results for Bilirubin are stated as conjugated (direct), unconjugated (indirect) . Higher level of bilirubin indicates different types of liver problems. Normal level of total bilirubin is 1.2 mg/dL (milligrams per deciliter) for adults, and usually 1 mg/dL for those under 18 and for direct bilirubin are generally 0.3 mg/dL. A bilirubin test…

biomedical engineering and Traditional Chinese Medicine pharmacology. In Dr. Junping Kou's lab, my teammate and I finished two research projects, my contribution to these projects including acquiring the funding, creating the mouse model of acute hypoxia-induced organs injury and ischemia-reperfusion injury, performing Western Blotting to measure protein expression level, providing evidence for the potential clinical application of Diosgenin. In my last year in undergraduate, I joined Dr. Haiyan…