Hypersensitivity

Anaphylactic disorder is one of the end result of immediate (Type I) hypersensitivity reaction. It starts when antigen (bee sting as in the patient’s case) binds to IgE antibody on the surface of mast cells that result of systemic release of vasoactive amines and other mediators from mast cells. The presence of IgE antibody indicate that this is not the first exposure to this antigen. The mast cells have a specific receptor for the Fc portion of IgE called FceRI (a high-affinity receptor). When…

Imagine you are in the class with a new student. Everything is quiet and everyone is working; all seems okay. All of the sudden, the student starts coughing. Not a big deal right? The coughing goes on for a while. The coughing soon gets worse and turns into wheezing. The student, breathless and red in the face, are not moving in their seat, nor are taking in full breathes anymore. Your teacher runs to the student and takes them out of the room. You can hear the student coughing, wheezing, and…

products to restore and save natural teeth. MI Paste is a topical tooth agent, which is currently indicated in the United States for the minimization of dentin hypersensitivity. The active ingredient in MI Paste, Recaldent (casein phosphopeptide (CPP) and amorphous calcium phosphate (ACP)), has been shown to clinically reduce dentin hypersensitivity by effectively altering the pattern of demineralization and remineralization that occurs. This paper discusses the processes of demineralization and…

“Hell in Isolation” In his short story, “The Fall of the House of Usher,” Edgar Allen Poe investigates the negative effects of self-isolationism. Roderick Usher, a mentally ill, incestuous, and secluded man, requests the narrator’s help. Upon his arrival, the narrator notices eerie attributes of the “melancholy” (3) house of Usher, while walking through clouds of miasma. The narrator then witnesses Roderick’s extreme paranoia, which stems from his solitude. The narrator also catches…

It takes 15-20 to take effect and lasts for 4-8 hours. Salicylates cross the blood brain barrier. It is metabolized in the liver and excreted in the urine. Side Effects Hypersensitivity to aspirin type drugs are to an accumulation of prostaglandins, after pathways break down prostaglandins are blocked. Inhibition of prostaglandin synthesis may result in some serious side effects like peptic ulcers, and problems with blood clotting…

eosinophilia and organ involvement/dysfunction in which other clinical entities have been excluded[9]. Eosinophilic hepatitis develops in response to some medications and to helminth parasites. We present a case report of a patient with drug induced hypersensitivity with subsequent eosinophilia with pancreatitis, hepatitis and gastritis. We will also discuss conditions with eosinophilia and review the…

contributions of the peripheral nervous system to Autism Spectrum Disorders (ASDs) using a mouse model of ASD. A recent study in our lab found a peripheral somatosensory neuron locus of dysfunction in two mouse models of ASD that lead to tactile hypersensitivity due to deficits in GABAA receptor signaling at the primary afferent terminals in the spinal cord, as well as anxiety-like behavior and social interaction deficits in these mice. These results highlight a possible new therapeutic target…

Hypotension, chest pain, dizziness, syncope, headache and cough Warfarin • It inhibits the synthesis of vitamin k dependent clotting factors by inhibiting vitamin k-2,3 epoxide reductase. • The main side effects include: alopecia, bleeding and hypersensitivity 5. Give at least 5 examples of “look alike/sound alike” medications. Hydralazine and hydroxyzine Dopamine and dubutamine Bupropion and buspirone Prednisone and prednisolone Epinephrine and ephedrine 6. Give examples of methods to…

Title: Effectiveness of Auditory Evoked Brain Potentials in diagnosis of hyperacusis and phonophobia in a case with Williams Syndrome. Introduction: Williams Syndrome (WS) is a neurodevelopmental disorder associated with a hemizygous deletion on chromosome (7)(1), . It is caused by the submicroscopic deletion of 1.5 to 1.8 Mb on chromosome 7q11.23(2), including the general transcription factor ill gene which encodes TFII-I which suppresses cell-surface accumulation of transient receptor…

Physical therapy is a type of treatment that many individuals may need when they are experiencing health problems that make it hard for them to move around or do daily task that they once were able to do on their own. The goal at any Physical therapy center is to help a patient get back to their normal range of motion such as restoring or increasing their flexibility, strength, endurance, coordination, and/or balance. (Physical Therapy) A patient can also be refer to a physical therapist to help…