Huntingtin

Huntington’s disease (HD) is one of many neurological conditions that exist and is prevalent in about 7 people per 100,000 (Lundy-Ekman, 2013, p. 245). It is more commonly seen areas of a predominantly white population, such as Europe, North America, as well as Australia, due to a higher frequency of certain alleles that are repeated in these populations (Walker, 2007, p. 221). This disease is classified as a neurodegenerative disorder, which is a term that is used to describe CNS…

Area of Study 3 – Investigating an Issue • How is Huntington’s Disease inherited and what are the consequences and treatments for this genetic disorder? -------------------------------------------------------------------------------------------------------- Huntington’s Disease is a specific neurological condition that affects the brain and nervous system. This specific disease is inherited by an autosomal dominant pattern meaning a single copy of the altered gene in each cell may cause the…

disease is a hereditary disease caused by a dominant gene in the 4th chromosome. There is a defective gene located on that chromosome that has a repeated sequence that codes to be an amino acid glutamine. This sequence will create the protein known as huntingtin or Htt. Htt interrupts the functioning of the ubiquitin-protease system resulting in dying of cells that occurs because of the activation an enzyme. Currently there is no effective treatment for Huntington’s disease. However the antibody…

Huntington’s Disease Huntington’s disease is one of the most dreaded diseases among the group of genetic diseases. Huntington’s affects the basal ganglia portion of the brain it is reasonable for a person’s motor functions. Over time huntingtin’s destroys this area. The disease’s name is derived from the ancient Greek word dance. It is named this because after the portion of the brain is partially destroyed, the person walks with an unintentional sway, an almost dance like movement. (Blachford)…