Homocysteine

The amino acid, homocysteine, is basically a cysteine with an added methylene bridge. Methionine, an essential amino acid, gives rise to homocysteine, a sulfur-containing amino acid, through the methionine cycle. Methionine is converted to S-adenosyl methionine (SAM) when an adenosine group from ATP is added on to activate methionine’s methyl group. SAM is a methyl donor that is a substrate used in many reactions. When it donates the methyl group, SAM is converted to S-adenosyl homocysteine (SAH). SAH is rapidly converted to homocysteine by removal of the adenosine group. Homocysteine is an important intermediate and can take a couple of pathways. It can either be converted back to methionine in a transmethylation reaction or be used to make other sulfur-containing amino acids.…

The effects of estrogen replacement therapy on the cardiovascular system have been debated for a while. Elevated levels of homocysteine even to a mild or moderate degree have been associated with an increased risk for CVD. A recent meta-analysis revealed a graded and linear relationship between increased cardiovascular risk and elevated homocysteine levels. (Yuksel et. al, 2011). Estrogen replacement was given to the surgically induced menopausal women evaluating the levels of homocysteine. A…

of almost every system in your body. It occurs billions of times per second; it helps repair your DNA on a daily basis; it controls homocysteine (an unhealthy compound that can damage blood vessels); it allows the recycling of molecules necessary for detoxification; and it helps maintain mood and keep inflammation under control. To maintain the proper functioning of methylation you need an optimal level of B vitamins. Without sufficient B vitamins, the methylation breaks down, and the…

What Is Vitapulse? Vitapulse is a supplement that is designed to improve heart health. It is filled with antioxidants that lower blood pressure, balance cholesterol levels and enhance cardiovascular function. Vitapulse can also reduce inflammation, which can lead to a number of health problems. What Does Vitapulse Have In It? Vitapulse has coenzyme Q10, PQQ and NAC. Coenzyme Q10 helps the body create ATP, which is the body's chief energy source. Coenzyme Q10 levels naturally lower as one gets…

MD There are increasing number of recent publications that recognized the similarity between TTP and B12 deficiency, and that TTP may mask B12 deficiency as the initial diagnosis. It had been hypothesized that hemolytic anemia may be more prominent in individuals with co-existing methylene tetrahydrofolate reductase (MTHFR) gene mutation and vitamin B12 deficiency associated with elevated homocysteine levels, often manifested in the peripheral blood smear as schizocytes. While TTP…

caused by the death of neurons in the mind, this antioxidant can help. A diet rich in oil-based salad dressings and nuts can ensure that individuals consume enough vitamin E. Avocados Avocados are amazing for mental health because they are high in monounsaturated fat. This helps to stimulate blood flow to the brain, and avocados can help to lower the blood pressure. Both benefits can help to boost overall brain health. Leafy Vegetables For optimal nutrition, aging adults should eat…

to prove whether the link is to be taken into consideration or not. Other agents such vaccines, secretase inhibitors, and anti--sheet conformational agents are being developed specifically as a prevention of Alzheimer’s. Nutriceuticals • Vitamins E and C Vitamin E and Vitamin C are 2 of the most common antioxidants. The pathological events of Alzheimer’s disease are thought to be linked with the oxidative mechanisms (Behl,1999). Intake of antioxidants have been shown to decrease…

In recent years MTHFR has been popularised in social media and blogs with various levels of information and potential misinformation. A search on google.com.au using the term “MTHFR” provided 1,330,000 results in 0.40 seconds.[1] With all of this different information being available 24 hours per day, all year round, it can be confusing for practitioners and patients to sift through to determine what is scientific, clinical or “hearsay”. 5,10-methylenetetrahydrofolate reductase (MTHFR)…

Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. The American journal of clinical nutrition, 80(6), 1611-1617. Article Summary Introduction Autism covers complex neurodevelopmental disorder usually evident in the early stages of childhood and is believed to be influenced by genetic and environmental factors. Abnormal metabolism regarding methionine and homocysteine are linked with another neurologic disease although the evaluation of…

was discovered last even 50 years later. These substances have a broad spectrum of activity and the key to cell metabolism, so experts are called guardians of the brain, nervous system, muscle tone, skin... They give us energy, help digestion, and contribute to strengthen hair, eyes and liver. Guardian of the heart and blood vessels Many talk about the fact that food is important for heart health, but it is known that some vitamin B complex play an important role in this process. In fact, some…