Hemolysis

Blood is everywhere, in everyone, in all living animals. The type of blood and what makes it look how it does is all based on its composition. The uses of it are vital to all animals survival as it is the key component to living. Unknown to most, but the blood's composition must be kept at near perfect balance at all time for it to perform all its functions. Blood is a crucial part of an animal's existence. Without it, it could not survive. Blood has numerous types as well as appearances, and…

guanylate cyclase, and as a result of this reaction a fetal hemoglobin will produced (Platt, 2008). Therefore, hydroxyurea overcome the bad effects of sickle hemoglobin (HbS), which causes a damage of the cell membrane by different ways leads to hemolysis and the loss of endogenous nitric oxide, on red blood cells (Platt, 2008). Hydroxyurea had excellent oral bioavailability and a half-life ranging from 2-4 hours which means a relatively rapid clearance in both adult and children (Ware et al.,…

Introduction Streptococcus pyogenes is a bacteria responsible for a wide range of diseases. They include pharyngitis, impetigo, a skin infection, scarlet fever, rheumatic fever, and toxic shock syndrome (TSS) (Burch, 2008). However, the focus of this research will be on necrotizing fasciitis (NF). Although necrotizing fasciitis is rare, it can be lethal. It is commonly known as “flesh-eating bacteria” (touching base, 2001) for its ability to destroy the skin tissue. For the most part, it is…

Abstract Sickle cell disease is an illness in the blood that normally affects people of African American descent, as well as people of Mediterranean and Middle Eastern origin. There are numerous types of sickle cell disease. The three most common are HbSS, HbSC and HbS Beta Thalassemia. There are also rare types such as: HbSD, HbSE, and HbSO. Sickle cell disease is an inherited disease. It is caused by receiving two abnormal genes from both parents, who either have the disease themselves or are…

To what extent does Hydroxyurea work to treat Sickle Cell Anaemia? Problem: Suffering From Sickle Cell Anemia. Sickle cell anaemia is a severe hereditary disease when there is an inadequate amount of erythrocytes (red blood cells) or haemoglobin in the erythrocytes. Haemoglobin beta alongside alpha globin makes haemoglobin which contains 146 amino acids. Haemoglobin beta makes up 98% of the total haemoglobin, whilst alpha globin makes the remaining 2%. Haemoglobin beta protein is produced by…

1 Cardiopulmonary bypass (CPB) 1.1 Introduction Cardiovascular diseases are the leading cause of death globally. Different types of cardiac operations are performed every day in hospitals varying in complexity to treat several lesions such as coronary artery bypass graft, heart valve replacement and total heart replacement. Cardiopulmonary bypass (CPB) is a crucial technique employed in the majority of these operations (Punjabi and Taylor 2013). It takes over the function of the heart and…

Running head: TRANSFUSION 1 TRANSFUSION 2 Transfusion-related acute lung injury (TRALI) is an under-reported, life-threatening complication of blood component transfusion due to the misinterpretation of symptoms, unfamiliarity of causes, and delay of standardizing methods of prevention. According to Mazzei, Popovsky, & Kopko (2008, 734), TRALI is characterized by symptoms indistinguishable from acute respiratory distress syndrome (ARDS) and…

About blood Functions Blood is the biological fluid in our body that transports nutrients and oxygen to the cells, and also exports the metabolic waste product away from the cells. To ensure the supply of oxygen needed by our organs and tissues, there are four important steps: 1. The oxygen must be transferred from our lungs into the blood plasma 2. The oxygen is stored on the hemoglobin in the red cells 3. The oxygen is transported to our body cells via circulation. 4. The oxygen is released…

Living With Sickle Cell Anemia Chasta D. Jones Text College Living With Sickle Cell Anemia Sickle cell anemia is a condition where there is not enough healthy red blood cells to carry enough oxygen within a persons body. The red blood cells become rigid, sticky, and shaped like crescent moons or sickles. The cells irregular shapes can get stuck in the blood vessels causing blockage of blood flow though the body. The sickle cells become weak and break apart and die. This leaves…

moderate pain, fever and prophylaxis of transient ischemic attacks and myocardial infarction. Side effects include: tinnitus, gastrointestinal bleeding, dyspepsia, epigastric distress, nausea, abdominal pain, anorexia, hepatotoxicity, vomiting, anemia, hemolysis, increased bleeding time, anaphylaxis, and…