Hemoglobin

1. Given the following amino acids, explain where they would be found in the tertiary structure of a protein and WHY (lack of explanation/incorrect explanations will NOT receive full credit; assume living system of pH = 7.4). Arg Phe Pro Glu His Ala Tyr Val Cys Arginine: This is a charged amino acid that is extremely hydrophilic. It is hydrophilic because while it has an aliphatic side chain that is hydrophobic, it also has two groups where a positive charge resonates between the two…

Introduction Anemia: A hemoglobin (Hb) concentration 2 SDs below the mean Hb concentration for a normal population of the same gender and age range. as defined by the World Health Organization, the United Nations Children's Fund, and United Nations University (Van Vranken ; 2010 .( Causes of anemia are many, but with a thorough clinical information and laboratory evaluation, a specific diagnosis can usually be established. The use of the mean red cell volume (MCV) is a standard diagnostic…

the hospital. His chest pain had resolved prior to arriving in the ED. His medical history is significant for atrial fibrillation, congestive heart failure, hypertension and he has age related macular degeneration. It is to be noted that his hemoglobin is 8.5 and 26.4. On admission he does have a BUN of 29. Cardiac enzymes are negative. He is known to be in atrial fibrillation. He is on Coreg, Digoxin and Pradaxa. It is to be noted in…

The RBCs of a patient with sickle cell disease has 40% abnormal beta hemoglobin chains which form the hemoglobin S (HbS), inherited from one or both parents thus possessing two of these alleles and a total hemoglobin of “80-100%.” A carrier of this genetic disorder would have one HbS and HbA allele. In decreased oxygen conditions, the RBCs of the SCD individual “assume a sickle shape, become…

causing an abnormality or mutation in the hemoglobin of red blood cells. The most common type of genetic blood disorders is sickle cell diseases with sickle cell anemia being the most dangerous (Addis, 2010). Sickle cell anemia is characterized into the group of sickle cell diseases. The phenotype number for sickle cell anemia is #603903 on the HBB gene/ locus (OMIM, 2014). Sickle cell anemia can also be known as HbS disease, hemoglobin S disease, and hemoglobin SS disease (NHLBI, 2012). Sickle…

Anaerobic and aerobic exercise were determined to effectively influence muscle oxygen uptake at the cellular level. Evaluating and measuring the effectiveness of the two types of exercise on oxygen uptake would inform the advantages and disadvantages they have on muscles. Significant amounts of oxygen are consumed by the human muscles when moderate intensity aerobic work is performed. Contradictorily, anaerobic exercise causes the body to break down stored glycogen in muscles for energy.…

important complement-regulating proteins. Due to this missing protein, the red blood cells are prematurely destroyed, which leads to hemolytic anemia. Hemolysis by the complement system leads to episodes of hemoglobin in the urine, which would then be considered hemoglobinuria. Hemoglobin is an iron-containing…

Complete Blood Count (CBC) Jenae Matson WCCC Laurel/Spring 2015 Anatomy and Physiology 2 Matthew Sisak January 23, 2015 Background: Blood is the most important part of your entire body because nothing will function without blood. Blood is there carrier of most important proteins and gasses in your body. Blood has a major part in clotting, protection form unwanted pathogens, passage of oxygen to the body and blood also maintains a balance of fluids, temperature, pH balance and acidic…

Sickle Cell Anemia is a birth defect that is “a genetic blood disorder caused by the presence of an abnormal form of hemoglobin” according to MedicineNet.com. Sickle cell is common to people that have ancestry with Africans. Sickle cell affects about 100,000 Americans, one out of every 365 African American babies, and one out of every 16,300 hispanic babies. Older children and adults with sickle cell disease may experience a few complications, or have a pattern of ongoing problems that make…

Skin color is determined by five main pigments; melanin, keratin, melanoid, hemoglobin, and oxyhemoglobin. According to most researchers skin color first evolved from the Africans when they migrated to Asia and Europe. Human skin color is very diverse; it ranges all the way from dark brown to white. The Human Genome Project is one of the most known experiments to help scientists map the genome both physically and functionally. Human skin acts as a physical barrier that protects chemical and…