Haemophilia A

Hemophilia Hemophilia is a rare hereditary bleeding disorder where the blood cannot clot normally at the site of a wound or injury. Where someone who has a minor cut can profusely bleed, and it can get so bad that it could end up making them sick. There are two types of hemophilia, Type A and Type B. Type A: Is the most common type, it is caused by lacking Factor VII, which is one of the proteins to help blood form clots. Type B is caused by lacking Factor IX. Hemophilia is normally diagnosed…

Hemophilia is a genetic disease that causes an affected person to severely bleed if cut. Lucky for hemophilia patients, gene therapy is an option. Gene therapy is a form of therapy during which selected healthy genes are transferred to an affected person’s cells. Not only is gene therapy a breakthrough in genetic engineering, but it can effectively cure genetic disorders such as cystic fibrosis and SCID and some acquired diseases like cancer. Gene therapy is carried out by packing a section of…

One in every five thousand males are born each year with a genetic condition called hemophilia. Hemophilia is a blood disorder that can cause severe bleeding both internally and externally due to having little to no clotting factor. In rare cases, hemophilia can occur in females or even be obtained. Hemophilia exists in two forms – hemophilia A and hemophilia B. Hemophilia A and B are caused by a defect in the genes F8 and F9, respectively. The F8 gene is responsible for making a specific…

Genetic Disease Summary: Hemophilia A Hemophilia is an inherited bleeding disorder that slows down or prevents the blood clotting process. There are two main types of hemophilia: hemophilia A and hemophilia B. Hemophilia A, which is known as classic hemophilia, is caused by a mutation in the F8 gene. People with hemophilia often display excessive bleeding, including bleeding in the stool and urine, though it is usually painless. Joints are also heavily affected, causing swelling and decreased…

Hemophilia Hemophilia is a bleeding disorder in which blood doesn’t clot normally and results in excessive bleeding. The Jews were the first to recognize hemophilia and was described in the Talmud, which is a collection of Jewish writings, and stated that if two brothers had died after getting circumcised the next male baby from that family didn’t have to go through the procedure. Years later in 1803 a physician named Dr. John Conrad Otto in Philadelphia discovered that the disease was…

Hemophilia Research Paper If you get a small papercut, it’s no big deal. Yes, it will hurt for a few minutes, but in a few days it’ll scab over, and be just fine. Unfortunately, it’s not the same case for everyone. There are many blood disorders, but one of the most common is hemophilia. Hemophilia affects over 200,000 people in the US each year. It causes the subject’s blood to not be able to clot properly, and leads to excessive bleeding (external and internal). The excessive…

According to the Center for Disease Control and Prevention, Hemophilia affects 1 in 5,000 male births which factor out to be about 400 babies born with hemophilia each year [3]. Hemophilia is classified as one of the oldest and longest lifelong bleeding disorders that are inherited, meaning passed down from parents to their children. This disorder occurs when the protein in the blood or platelets that assists the blood to clot is absent or not functioning properly, resulting in extended bleeding…

Hemophilia is a genetic blood disease, which is symbolized by the importance of blood to clot, or compact even from inconsequential damage. Blood clotting and sudden gene mutation factor in the development of this disease. This disease is generated by an inadequacy of blood multifaceted called factors Therefore, with the nonappearance of factors, the blood clotting process is continued. There are two different types of Hemophilia, Hemophilia A and Hemophilia B. for example. Hemophilia A, the…

genetics of Haemophilia Both forms of haemophilia result from mutations on the human X chromosome, a similar sex-linked pattern of inheritance as colour blindness.2 Each son of a female carrier has a fifty percent chance of having the disease, and each daughter has a fifty percent chance of being a carrier. An affected male’s daughters will all be carriers as he will pass on the mutated gene to them all; while he sons will not be affected11 Queen Victoria must have been a haemophilia carrier in…

$1,159 million) and keep increasing mainly in the North America market. Moreover, the growth hormone therapy is mostly used in developed countries and there are estimated more than 2 million people have the medical needs (Novo Nordisk A/S, 2015). The global market for growth disorder treatment is about DKK16 billion (approximately $3 billion) and increases more than 2% annually (Annual Report 2013, Novo Nordisk). Norditropin® has a leading market share of 34%, in addition, the company has…