Guanine

PAI-1 is associated with the impairment of vascular wall and endothelial dysfunction. (4).Human PAI-1 gene is located at chromosome 7q22, and various genetic polymorphism have been identified in its promoter region (4). A common insertion/deletion of guanine have been seen in this region (3). The deletion of the allele (4G) is associated with increased PAI-1 plasma level due to inability of transcriptional repressor protein for binding to this polymorphic sequence (5). C - reactive protein (CRP)…

The book I read for my Biology book report was, The Double Helix, A Personal Account of the Discovery of the Structure of DNA an autobiography written by James D. Watson. It was released in 1968 and was published by Atheneum Press (US), Weidenfeld & Nicolson (UK) and is 226 pages. As the title suggests, the book is Dr. Watson’s personal account of the groundbreaking discovery of the structure of DNA. Biologists already knew that genes were the material responsible for traits getting passed from…

Introduction Over the past few years, there is a worldwide increasing tendency for the consumption of functional foods, including probiotics, prebiotics or both. Influenza epidemics cause numerous deaths and millions of hospitalization each year. Because of the alarming emergence of resistance to anti-influenza drugs, there is a need to identify new naturally occurring antiviral molecules. Punicaceae has been used for centuries in many cultures for the prevention and treatment of a wide…

Ways to discover biological immortality and slowing down ageing process Ageing is simply the matter of our bodies physically getting old and it has environmental and genetic causes. As we get older we tend to develop and maintain some habits which can affect our health either positively or negatively and this represents the accumulation of changes in a person over time. Biological immortality is a term used by biologists to distinguish cells that are not subject to the Hayflick limit. There are…

Laboratory Exercise #12: Human Genome Project Elena Zachel Part 1: The Human Genome Project 1.The main goals of the HGP (Human Genome Project) are to establish all the 20,000-25,000 genes in human DNA, find out and understand the order of the 3 billion chemical base pairs that make up human DNA, save the information of human DNA in databases, enhance tools for data analysis, move similar technologies to the private sector, which means that it would not be owned by the government, and last…

DNA profiling is a fast paced technology that allows DNA to be sampled and connected to the identity of one person. One of the main uses for DNA profiling includes finding DNA at crime scenes and having the ability to work out the events that may have occurred (Better Health, 2015). This process includes the collection and sampling of DNA found at the scene of the crime to those who are suspected to have committed a crime. In Australia in 2011, 60% of those held in custody have previously been…

One of the greatest gifts from God to humankind is biology. From the Greek words which mean the study of life, biology is a branch of science that focuses on how living things works. For example, how does a tiny human being turns into a full-grown adult in just matter of time? Why are there twins that look exactly alike but there are some that are not exactly alike? Thanks to biology, scientists now are able to answers these questions. It is all in the genes or more accurately the…

his or her mother, while the other 19 are inherited from his or her father. DNA is tightly coiled inside of each chromosome, and the chromosomes contain genes which are comprised of proteins and nucleic acids, specifically Adenine (A), Thymine (T), Guanine (G), Cytosine (C ), and sugar-phosphate. This DNA coding determines genetic differences between kittens, such as sex, eye color, fur color, markings, and more. As previously mentioned, half of a kitten’s chromosomes are inherited from their…

last types of mutations to occur and cause DMD 15-30% of cases. Point mutations are adjustments in the DNA sequence which are caused by a change in the nucleotide by an insertion or a deletion. The four nucleotides include Thymine (T), Adenine (A), Guanine (G) and Cytosine (C). When insertions occur, nitrogenous bases are added to the DNA sequence meaning it is a few bases longer than it should be. When a deletion occurs, a few bases are removed meaning the DNA sequence is shorter than normal.…

Started in August/2014, I have been participating in brain tumor researches. I authored a poster showing the role of methylation of the gene O (6) -methyl guanine-DNA methyl transferase (MGMT) on the resistance of the tumor cells to the standard treatments and how regulating that gene could affect malignant cells’ sensitivity. It was under the name of “MGMT-targeted therapeutics of glioblastoma: Unexplored…