Glioma

Vinorelbine also known as Navelbine® is an anti-cancer chemotherapy drug. It belongs to a class of chemotherapy drugs called vinca-alkaloids; which can be categorised as spindle poisons1. Vinorelbine and Vindesine are semi-synthetic derivatives from the first generation of vinca-alkaloids; Vinblastine and Vincristine2. These original vinca-alkaloids were derived from dried leaves of the Madagascan periwinkle (vinca rosea) plant1. Madagascar periwinkle is also used in the treatment for diabetes,…

are not known, but through research, it has been discovered that people who work with rubber or certain chemicals have a greater risk of a tumor. There are over 120 types of brain cancer, both Gliomas (malignant or benign that originate from glial tissue) and non-glial tumors. The two most common types of Glioma are astrocytomas and ependymomas.non-glial tumors including medulloblastomas, meningiomas, schwannomas, and childhood brain tumors. The Concern with prevention Potential causes are still…

Neurofibromatosis The genetic disorder I chose is called Neurofibromatosis. There are three types of Neurofibromatosis: Type 1 (von Recklinghaus disease, peripheral NF, Recklinghausen neurofibromatosis), Type 2 (bilateral acoustic NF, central NF or vestibular NF), and schwannomatosis. Schwannomatosis used to be considered a variation of neurofibromatosis type 2 but is now recognized as different from neurofibromatosis type 2. Neurofibromatosis types 1 and 2 are autosomal dominant traits.…

Any tumor that arises from the supportive tissue or glial cell, of the brain is called a “glioma” [8]. Astrocytoma is the one type of glyoma. It is named after astrocytes. Astrocytes are star-shaped cells from which they grow.According to the degree of abnormality Astrocytomas are graded in to I to IV classes [8] .These classes are Pilocytic Astrocytomas (PA) , Diffuse Astrocytoma, Anaplastic Astrocytomas(AA) and Glioblastoma Multiformeor( GBM) . Pilocytic Astrocytomas are generally slow growing…

ATF3 function in cancer cells: oncogene vs. tumor suppressor The mouse homolog of ATF3 (named TI-241) was identified by differential hybridization due to its high expression in the extremely metastatic melanoma cell line B16-F10, and absence in the related but non-metastatic cell line B16-F1. While characterizing the ATF3 mouse homolog, it was found that over-expression of ATF3 in the non-metastatic B16-F1cells converted them into highly metastatic cells, therefore, suggesting that ATF3…

The cellphone has brought many advances to our society and has become ingrained into our generation. However, looking at these advances, are these certainly all good? Looking back forty to fifty years ago the cellphone was just in its early stages of development. Only a few select amount of people could use this device. Now in the year of 2015 walking around anywhere mostly everyone has a cellphone in their hand. The cellphone today has several uses such as texting, internet, applications of…

According to scientists, cell phones were marked as “possibly carcinogenic.”(Trottier 1 ) In other words, it means that there may possibly be a link between the use of cell phones and cancer. However, too little time has passed to detect if cell phones can cause cancer, researchers found no evidence of a link between cell phones and brain tumors and there is no evidence from studies that radiofrequency can cause cancer. More and more evidence is showing up that cell phones do not cause cancer.…

to develop inherited negative opinions regarding its use. Patient History & Diagnosis As per WHO classification, Glioblastoma Multiforme (GBM) (Grade IV astrocytoma) is the most prevalent malignant brain tumour in adults accounting for 54% of all gliomas.(1, 2) It’s associated with poor-prognosis with approximately one-third of…

Research Question: Do the health risks from using cell phones over power the necessity for them in modern times. Introduction: Everyone has been told that mobile phones pose a great health risk to them, and that they are one of the main causes of cancer, but is this really true? Are mobile phones as bad a health risk as we are made to believe? Billions of people around the world are connected due to mobile phones, which means that billions of people face the supposed dangers that mobile phones…

that current cell phone usage may cause brain cancer, modern, third-generation phones emit, on average, about 1% of the energy emitted by the GSM phones that were in use when epidemiological studies that observed a slight increase in the risk for glioma – a malignant type of brain cancer –among heavy users of wireless and cordless telephones were…