Genetic predisposition

A prion is a infectious protein agent and the specific name of prion in BSE is PrP scrapie(PrPSc). The normal protein that is being acted upon by the protein is called cellular prion protein(PrPc). Prions are a problem because they are an abnormal form of a normal protein that is misfolded without an immune response. The strings of amino acids are put together to make proteins inside cell. Then they are then pushed together and folded into a framework letting them function properly. These prion…

Huntington’s Disease What is Huntington’s? A family passed down disease which is an autosomal dominant trait characterized by the onset of Chorea and Dementia after the ages of 40-50? Signs of initial onset of the disease include paranoia, poor impulse control, depression, hallucinations, and delusions. Over time, there will be an intellectual impairment, loss of fine motor control, athetosis, and diffuse chorea involving axial and limb musculature develops. Normally, an individual will end up…

1000 somatic cells as an adult, C. elegans is amenable to genetic crosses and produces a large number of progeny, at times even exceeding 1000 per adult, with a life cycle of up to 3 days, under optimal conditions There are two known sexes of C. elegans, a self-fertilizing hermaphrodite (XX) and a male (XO). Self-fertilization of the hermaphrodite leads to genetically identical progeny…

In the Achieve 3000 article “China and Japan: Can Animals Sense Trouble?” talks about the argument of whether nature and animals can or cannot predict and warn us of when a disaster is about to happen. This article provides reliable evidence for both sides of the topic that will help you decide which side you will be on. Evidence that is for animals can predict is from this article is a quote by seismologist Roger Musson: “there are several possible reasons for behavioral changes in animals…

Rad8 is a conserved protein, it was previously reported to be sensitive towards both UV and gamma irradiation during G1/S period in Schizosaccharomyces pombe (Doe et al., 1993). It consists of three conserved domains, including E3 ubiquitin ligase motif, SNF2 helicase domain, and a family specific HIRAN domain. Rad8 is required for error-free post-replication repair by contributing to polyubiquitylation of proliferating cell nuclear antigen (PCNA). Up-regulation (12.52-fold) of Rad8 indicated…

Having freckles is a common and harmless condition that is shared among many people around the world. Freckles are passed down genetically, and are a dominant trait. They are most common and most easily seen on fair skinned people. Many people with freckles notice that their freckles become darker after being out in the sun. This is because freckles are basically clumps of melanocytes, and the sun's ultraviolet rays cause melanocytes to create more melanin, making the freckles darker. Now,…

As for children that suffered the hearing loss at birth will have a harder time with comprehension and speech because of the temporal lobes auditory areas taking over the other functions of other senses. With them being no more than different from a hearing person because they do still bleed the same color blood as us. We can get around to what has actually happened to the development of the ear and what caused the auditory cortex to be shot. The diseases stated above such as Cytomegalovirus…

What is reality? Is there a connection to your brain and the world around you? Is it really what you think it is? Current knowledge about our bodies state that the brain sees the world by using millions of stimuli around us to perceive the feelings of cold, soft, bright, and countless others. Take a look at this sunset, you see the sunset in front of you but when you leave the area. Was there really a sunset at the time period. Your mind says yes since you recall being there but is there…

X chromosome rather than two. As the baby grows and the cells divide, the X chromosome will be missing from every cell of the baby's body. In some cases, both X chromosomes are present, but one is abnormal. It may be shaped differently or missing genetic material. The effects of the condition vary widely among girls with Turner syndrome. It all depends on how many of the body’s cells are affected by the changes to the X chromosome. The abnormality is not inherited from an affected parent (not…

It can be argued that “… the origin of life is the origin of replication” (Lane, 2010). This statement proves to be correct to a certain extent as if there were to be any mutations within the stages of replication, the life created could have abnormalities which may decrease quality of life experienced. Sickle cell anaemia is a hereditary form of anaemia in which a point mutation causes the formation of haemoglobin which distorts the erythrocytes into a sickle-shape (Appendix 1). The sickle…