Gene Yang

advantage of CRISPR is its ability to target multiple targets at once. In early 2013, heterologous expression of the CRISPR-Cas9 system and all of its parts was demonstrated in mammalian cells. The modified bacterial system was also able to insert genes at various target locations in the mammalian genome by expressing a multiple target spacer array (Cong et al., 2013). The system was expressed in mammalian cells with varying combinations of codon optimized Cas9 (spCas9). spCas9 used a modified…

A genetically altered baby is something some people have only dreamed about, but now, it has become a reality. Scientist have discovered a way to alter human genetic traits and produce the perfect offspring. Some traits scientists have tried to alter include sex, eye color, and height, but it is still in the experimenting stage and should be possible within the next few years. Add more. Creating genetically altered babies should be prohibited. Genetically altering babies is still in the…

the disease, investigations were done to identify the gene that is linked with the disease. Some of the common approaches to do this was linkage analysis and positional cloning often involving the use of polymorphic DNA markers to identify the best candidate gene that can…

(2014) conducted GWAS of 282 soybean breeding lines for resistance to SCN HG Type 0 using the USLP 1.0 SNP arrays (Hyten et al. 2010). The authors detected a significant association between markers and the known gene regions but no novel regions were detected. Han et al. (2015) identified 19 association signals significantly related to resistance to SCN HG Types 0 (race 3) and 1.2.3.5.7 (race 4) as well as over 130 new sources of SCN resistance. Among the significant…

sequences that are capable of being edited out of genes. Using the CRISPR system, bacteria are able to destroy the genome of invading viruses and thus prevent the virus from being able to replicate and survive in its host.…

CRISPR Genes – A way to eradicate Autism to Cancer to Zellweger syndrome and everything in-between It was September 20th 2001. It was the day my mother would be screened if the fetus (i.e. me in my glorious self) showed an elevated risk for Downs Syndrome. A triple screen blood was performed which measured the quantities of three substances: Alpha-fetoprotein (AFP) which is produced by the fetus, human chorionic gonadotropin (hCG), and unconjugated estriol which is produced by the placenta. The…

Technology today now allows us to address the idea of cloning. Cloning is creating an identical genetic copy of an organism or a cell. The process of this is there will be three subjects A, B, and C a body cell will be taken from A, the DNA will be extracted then an egg cell will be taken from B the nucleus removed. The DNA from A is fuse with the egg cell from B the fused cell develops into an embryo when it is placed in C the surrogate and then the clone is of subject A. To get to cloning…

In this study, we analyzed the bulk of genomic and transcribed CsRn1 sequences encompassing the putative frameshift region in C. sinensis and Opisthorchis viverrini, which is a nearest phylogenetic neighbor of the liver fluke, to address the issue regarding the expression strategy of CsRn1. Our results demonstrate that CsRn1 copies lacking frameshifting have arisen from the precedential counterparts with two overlapping ORFs by a single-nucleotide insertion at an upstream region of gag stop…

and allow scientists to forgo constantly screening for mutations and allow dominant markers to be carried (Edgley, 2006). Stubble is located on Chromosome 3R at 3-58.22 (Duncan and Kaufman, 1975). It is a dominant gene. Unlike most genes that have this mode of inheritance, the Stubble gene is typically not homozygous lethal (Attrill,2016). Stubble bristles are fifty percent the size of Wild-type…

eugenic policies that promoted the manipulation of their children’s genes. After viewing this film, it is difficult not to conclude that any form of gene editing technology only leads to a dystopian future in which genetic discrimination rules supreme. We must despise any potential Nazi-esque policies that Vincent Freeman had to suffer through as a result of the eugenic ideal of his society. The obvious enemy of humankind is this gene editing technology…