Gene therapy

expressing the same set of genes to carryout functions that they have to do as a tissue; a causality of cells having a common ancestor or a progenitor cell which can be sourced at one point in time of development of an organism. This expansion of one cell into various clones occurs via a process called clonal expansion. The process is not different in cancer cells, there is one cell which would have acquired a mutation, or inherited an additional copy of a gene or lost the copy of a gene which…

create a perfect baby or conceive your baby naturally? Researchers have been saying that parents will be able to choose their child’s genes. This can be done by placing a sperm and an egg on a plate to be observed and modified. By PGD, preimplantation genetic diagnosis, and genetic therapy, human embryos can be checked for genetic defects and can be inserted genes that treat diseases. Of course, parents will always want their children to be healthy and successful. Being able to create designer…

history and family history is looked into, and usually with this information it is easier to tell if the person has the gene. Although, tings can get difficult when the patient does not know the parent or the parent has died. Autopsies are sometimes required and medical history is looked at. When the doctors look at the DNA they look for “…CAG- repeat of at least 36 on the Huntington gene on chromosome 4 (Roos, 2010 pg 5).” This should give the doctors an easy answer does the patient have…

A. Polymerase chain reaction (PCR) Principle It includes the primer mediated enzymatic amplification of DNA. It uses the ability of DNA polymerase to manufacture new strand of DNA complementary to the offered template strand. DNA polymerase can add a nucleotide only onto a preexisting 3′-OH group to add the first nucleotide that is way Primer is required. Then DNA polymerase elongates its three ends by adding more nucleotides to generate an extended region of double-stranded DNA.…

Stickler Syndrome is a rare disease due to several mutations in certain types of genes that are involved in the formation of collagen. Collagen is an important building block of connective tissues, which is mostly effected throughout the body by Stickler Syndrome. This disease affects both male and female; the rate is at approximately one to three in every ten thousand births and one within every seventy-five hundred births. Investigators of this disease believe that Stickler Syndrome is very…

Huntington’s disease: Germline Therapy Huntington’s disease is an inherited disease that causes progressive breakdown of the nerve cells within the brain (Staff, 2015). There is usually a late onset associated with the disease were there are not any signs or symptoms until 30s or 40s (Staff, 2015). It is possible for the disease to appear earlier in life known as juvenile Huntington’s disease, which occurs in the 20s (Staff, 2015). Each one of these types has its own type of presentation with…

Osteopetrosis is a clinical syndrome characterized by the failure of osteoclasts to resorb bone. As a consequence, bone modeling and remodeling are impaired. The defect in bone turnover characteristically results in skeletal fragility despite increased bone mass, and it may also cause hematopoietic insufficiency, disturbed tooth eruption, nerve entrapment syndromes, and growth impairment. Researchers have described several major types of osteopetrosis, which are usually distinguished by their…

then visited Dr. Adrian Thrasher to talk about gene therapy. Gene therapy consists of man made copies of healthy CF genes in a fatty liquid. It said that in gene therapy the first thing they do is they identify one gene that is not performing it’s purpose. Next they insert a healthy gene to do the job. Reese Evans was a boy that was born without an iffetive immune system and he was the first person that they decided to do gene therapy. Gene therapy is what ended up saving Reese’s life. The…

Due to the advancement in gene therapy, it can be done to germ cells to avoid further generations to carry the disease. This can help a family because it will remove the defective genes in the sperm and egg cells before fertilization. Mr. and Mrs. Salomon just discovered that they each carry the disease for Tay-Sachs and do not know what is best for them. Their child is guaranteed to get Tay-Sachs and cannot be cured. They are not sure if it is right to try out this experimental germ cell…

A body is made up of cells, and in each cell, genes are found. Genes are passed down to children from parents, and over time genes can mutate. Mutations, or changes, in genes acquired from a mother or father, or genes damaged throughout a person’s life, is what contributes to the growth and development of cancer. Normally, one mutation will not cause cancer because the human body can correct that change, but with a multitude of mutations over time cancer becomes more probable. There have also…